SUMMARYInterfacial instability of a rotating miscible droplet with signiÿcant Coriolis force in a Hele-Shaw cell is simulated numerically. The in uences of the relevant control parameters are ÿrst discussed qualitatively by ÿngering patterns. More vigorous ÿngerings are found at higher rotational e ects, a lower viscosity contrast and a weaker e ective surface tension (Korteweg constant). For a time-dependent gap HeleShaw cell, a higher cell lifting rate makes the rotating droplet bear an inward straining ow, which leads to ÿngering enhancement. On the contrary, a higher pressing rate provides more stable e ects by additional squeezing outward ow. A quantitative analysis between the Coriolis e ects and tilting angles of ÿngers is addressed. For arbitrary combinations of all relevant control parameters, the values of tilting angles follow a nearly linear relationship with the Coriolis e ects. We estimate the correlation between the relevant control parameters (dimensionless Coriolis factor Re, viscosity parameter R, cell lifting rate a) and tilting angles (Â) of ÿngers that can be approximated as  = (0:0047 √ Pe=R+18:2a)Re for signiÿcant Korteweg stresses.