There are many flows driven by the rotation of one, or more, disks, and this paper is concerned with the instabilities of such flows, and their laminar-turbulent transition. The original, and most studied, rotating-disk flow is the von Kármán swirling flow produced by an infinite rotating disk in an otherwise still fluid. This flow shares many stability characteristics with three-dimensional boundary layers of engineering interest over aerofoils; most notably, the cross-flow instability giving rise to stationary cross-flow vortices. Various basic flows produced by rotating disks, and their stability, are reviewed, and motivations for assembling this special issue dedicated to the instabilities of rotating-disk flows are presented. The papers appearing in this special issue are discussed and related to major research themes in the field, and to one-another.