Rosai-Dorfman Disease of the Breast in a Male

Bansal, Pankaj; Chakraborti, Shrijeet; Krishnanand, Geeta; Bansal, Rohini

doi:10.1159/000325050

Cited by 12 publications

(8 citation statements)

References 9 publications

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“…The reported mortality is extremely low. In our series, spontaneous remission was seen in one middle aged male patient 6 months after initial diagnosis [7]. The risk factors for a poor prognosis include older age, concurrent immunologic dysfunction, systemic diseases, and involvement of vital internal organs such as kidneys, lung and liver [1,[24][25][26][27].…”

Section: Discussion and Literature Reviewmentioning

confidence: 90%

“…Immunohistochemical studies support the diagnosis [16]. Only a few of the reported cases of breast RDD were successfully diagnosed by ine needle aspiration biopsy and cytologic evaluation [7,8,[17][18][19]. Those diagnoses were based, primarily, on identi ication of the hallmark feature of emperipolesis.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

“…The ratio of female to male was 5.8 to 1. Among those reported cases of breast RDD, 4 cases involved skin, showing deep dermal and subcutaneous lesions [4][5][6][7]. Three cases involved intra-mammary lymph nodes [8][9][10].…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

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Rosai-Dorfman disease presenting as a breast mass

Dai¹,

Cai²,

Vohra³

et al. 2019

Arch Pathol Clin Res

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Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, fi rm and poorly defi ned lesion, which can radiologically mimic a breast cancer and is therefore an important differential consideration. The diagnosis of breast RDD is challenging, especially on a small biopsy specimen. We report a unique case of breast RDD with a literature review including common presentation, differential diagnosis, and recommended management. A high index of suspicion for this rare entity is essential to render a correct diagnosis, thereby avoiding unnecessary diagnostic tests and treatment.How to cite this article: Dai D, Cai Q, Vohra NA, Wong J, Therien ZP, et al. Rosai-Dorfman disease presenting as a breast mass. Arch Pathol Clin Res. 2019; 3: 008-014. https://dx.

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Section: Discussion and Literature Reviewmentioning

confidence: 90%

Section: Discussion and Literature Reviewmentioning

confidence: 99%

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Rosai-Dorfman disease presenting as a breast mass

Dai¹,

Cai²,

Vohra³

et al. 2019

Arch Pathol Clin Res

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“…The patients were aged 23, 35, and 59, respectively. The 59 year old presented with the only case of multiple masses in the left breast [7], [8], [9]. In addition to the 35 year old’s case, this is the only other one identified that presented in the right breast.…”

Section: Discussionmentioning

confidence: 99%

A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review

El-Attrache

Kapenhas

Morgani

et al. 2017

International Journal of Surgery Case Reports

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“…Due to its rarity, pathologic diagnosis of breast RDD is challenging, especially in a small biopsy sample with limited tissue. In this report, we discuss a case of breast RDD with a literature review [4][5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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2019

JGWH

View full text Add to dashboard Cite

Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, firm and poorly defined lesion, which can radiologically mimic a breast cancer and is therefore an important consideration. The diagnosis of breast RDD is challenging, especially on a small biopsy specimen. We report a unique case of breast RDD with a literature review including common presentation, differential diagnosis, and recommended management. A high index of suspicion for this rare entity is essential to render a correct diagnosis, thereby avoiding unnecessary diagnostic tests and treatment.

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Rosai-Dorfman Disease of the Breast in a Male

Cited by 12 publications

References 9 publications

Rosai-Dorfman disease presenting as a breast mass

Rosai-Dorfman disease presenting as a breast mass

A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review

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