A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review

Abstract

HighlightsRosai-Dorfman Disease is a benign disease of cervical adenopathy.Extranodal disease can present rarely in the breast.Histiocytes with emperipolesis is the hallmark pathological finding.Surgical excision with post-op observation is the treatment for breast lesions.Minimal amount of cases found in the male breast.

Mammary Extranodal Rosai-Dorfman Disease With and Without Associated Axillary Lymphadenopathy: Insights for Practitioners of Breast Pathology

“…4 Extranodal involvement of the breast is an uncommon finding. [7][8][9][10][11][12][13][14][15][16] RDD poses diagnostic challenges to radiologists and pathologists when it involves axillary lymph nodes and breast tissues because the disease can mimic mammary carcinoma with nodal involvement. Based on severity, some cases of RDD can be managed with observation alone, while others may require surgical, immunomodulatory, and/or antineoplastic therapies.…”

A rarity in breast pathology: First recurrent male case of Rosai-Dorfman disease

“…Extranodal disease to the breast is rare with 20–25 reported cases. Of those, only four are identified in the male breast [ 1 ]. This study is a follow up on “A Rarity in Breast Pathology: A Male Case of Rosai-Dorfman Disease and Literature Review” that was published in May 2017 in the International Journal of Surgery Case Reports.…”