Rosacea and Rosacea‐like Demodicldosis

Ayres, Samuel

doi:10.1111/j.1365-4362.1987.tb00894.x

Cited by 9 publications

(17 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As the mite is a normal inhabitant of the human Duration of treatment (months) pilosebaceous unit, the mere detection of mites in skin specimens has no clinical relevance. Only quantitative analysis can have pathogenic implications (4,21). Although skin surface biopsy has also false-negative results (22).…”

Section: Discussionmentioning

confidence: 97%

Density of Demodex folliculorum in Perioral Dermatitis

Dolenc‐Voljč¹,

Pohar²,

Lunder³

2005

Acta Dermato-Venereologica

View full text Add to dashboard Cite

The role of Demodex folliculorum in perioral dermatitis is not satisfactory explained. Our purpose was to assess the density of D. folliculorum in perioral dermatitis and evaluate the relationship of the mite count to previous therapy with topical steroids. A standardized skin surface biopsy of the chin was performed in 82 female patients with perioral dermatitis and in 70 control female subjects. Patients who received previous topical steroid therapy had a significantly higher mite density than the patients who had received no topical steroids (p<0.001). In the latter group of patients, the mite density did not differ significantly from that of the control group (p=0.629). Mite density increased significantly with the length of treatment with topical steroids (p<0.001). Our results suggest that increased density of D. folliculorum in perioral dermatitis is a secondary phenomenon, associated with topical steroid therapy.

show abstract

Section: Discussionmentioning

confidence: 97%

Density of Demodex folliculorum in Perioral Dermatitis

Dolenc‐Voljč¹,

Pohar²,

Lunder³

2005

Acta Dermato-Venereologica

View full text Add to dashboard Cite

show abstract

“…5 The density of Demodex mites can be studied by KOH preparations of follicular plugs, skin scrapings, and SSSB specimens. 18,30,33 In our series, the examination was performed in 11 patients, and only one had a negative result (3 mites/follicle). Forton and Song 34 found that when the first SSSB specimen was negative, a subsequent SSSB specimen from the same site had yielded more than 5 mites/cm 2 .…”

Section: Discussionmentioning

confidence: 99%

Demodicosis: A clinicopathological study

Hsu

Lee

2009

Journal of the American Academy of Dermatology

163

136

View full text Add to dashboard Cite

“…Of note, the photograph illustrating ' 'Persistent erythema (PE) with normal Demodex density (Dd)' ' is the same as that of subclinical demodicosis ' 'PE with high Dd' ' to stress that the clinical appearance/phenotypes of these conditions are identical. The patient with pityriasis folliculorum on black skin has provided written consent for publication Table 1 Comparison between pityriasis folliculorum and erythematotelangiectatic rosacea (ETR), and between rosacea-like demodicosis and typical papulopustular rosacea (PPR) Pityriasis folliculorum ETR according to NRS definition References Definition Etiological Clinical [6,101,102,105] Cause Demodex proliferation Inflammatory reaction? [6,101,102,105] Demodex density Similar [29,109,156] Histology Similar [31] Signs and symptoms Similar, mixed forms are the most frequent [6,97], Fig.…”

Section: Case Reportsmentioning

confidence: 99%

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

Forton¹

2020

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Rosacea is an inflammatory continuum, with all characteristics being already present from the onset of the disease, even if not clinically visible. Demodex proliferation also appears to be a continuum process in rosacea, and high Demodex density is beginning to be accepted as an important trigger of the inflammatory cascade and as a marker of rosacea: moreover, papulopustules of rosacea can be treated using acaricides. Immunological studies are providing new hypotheses according to which Demodex may induce tolerogenic dendritic cells and collaborate with VEGF to induce T cell exhaustion favoring its own proliferation. This proliferation may not be clinically visible initially. The interactions among VEGF, Demodex, and immunity need to be explored, and the nosology of rosacea definitions adapted accordingly. The effectiveness of treating any patient who only has visible vascular symptoms with an acaricidal cream needs to be confirmed in prospective controlled clinical trials with long-term follow-up, but it is already important to detect patients with pityriasis folliculorum among those with only vascular symptoms of rosacea in order to treat at least these patients with an acaricidal cream. DIGITAL FEATURES This article is published with digital features to facilitate understanding of the article. You can access the digital features on the article's associated Figshare page. To view digital features for this article go to

show abstract

Rosacea and Rosacea‐like Demodicldosis

Cited by 9 publications

References 6 publications

Density of Demodex folliculorum in Perioral Dermatitis

Density of Demodex folliculorum in Perioral Dermatitis

Demodicosis: A clinicopathological study

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

Contact Info

Product

Resources

About