Room-temperature atmospheric pressure plasma plume for biomedical applications

Laroussi, Mounir; Lü, Xing

doi:10.1063/1.2045549

Cited by 606 publications

(396 citation statements)

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“…Several recent reports suggest that atmospheric plasma jets could be formed through fast-moving plasma bullets. [8][9][10]15 Further investigations are needed to progress to these preliminary studies and to advance the current understanding of atmospheric plasma jets. In this article, we present an experimental investigation of fast-moving plasma bullets formed in an atmospheric dielectric-barrier discharge jet.…”

Section: Introductionmentioning

confidence: 99%

“…4,5 These plasma sources can be generated with sinusoidal excitation at 60 Hz, 6 kHz, 5,[7][8][9][10] MHz, 1,4,[11][12][13][14] and with repetitive nanosecond pulses at kilohertz. 8,15 For many of their applications, nonthermal plasma jets offer a useful practicality of separating the plasma generation region from the application region thus facilitating access to an extensive range of reaction chemistry. 7 However, possible mechanisms responsible for the production of atmospheric plasma jets remain largely unknown.…”

Section: Introductionmentioning

confidence: 99%

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A hypersonic plasma bullet train traveling in an atmospheric dielectric-barrier discharge jet

et al. 2008

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An experimental observation of fast-moving plasma bullets produced in an atmospheric dielectric-barrier discharge jet is reported in this paper. Nanosecond imaging suggests that the atmospheric discharge jet consists of a plasma bullet train traveling at a hypersonic speed from 7.0km∕sto43.1km∕s. Yet on a millisecond scale, the bullet train appears as a plasma jet of several centimeters long. The plasma bullets are produced through several possible mechanisms, the most likely of which is related to the ionization wave. Time and space resolved optical emission spectroscopy show that reactive plasma species can be delivered to different spatial sites with varying quantities.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A hypersonic plasma bullet train traveling in an atmospheric dielectric-barrier discharge jet

et al. 2008

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“…While its geometric details are given elsewhere, 17,18 its tubular structure and its use of dielectric barriers are different from the atmospheric pressure plasma jet, 19 the plasma needle, 20 and the plasma plume produced from a gas flow through two parallel-plate electrodes. 21 For future reference, it is referred to as the atmospheric dielectric-barrier discharge ͑DBD͒ tube jet or DBD-tube jet. For this study, the DBD-tube jet employed either helium or helium-oxygen mixture as the background gas.…”

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confidence: 99%

Protein destruction by atmospheric pressure glow discharges

Deng

Shi

Chen

et al. 2007

Applied Physics Letters

161

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It is well established that atmospheric pressure glow discharges are capable of bacterial inactivation. Much less known is their ability to destruct infectious proteins, even though surgical instruments are often contaminated by both bacteria and proteinaceous matters. In this letter, the authors present a study of protein destruction using a low-temperature atmospheric dielectric-barrier discharge jet. Clear evidences of protein removal are presented with data of several complimentary experiments using scanning electron microscopy, electron dispersive x-ray analysis, electrophoresis, laser-induced fluorescence microscopy, and protein reduction kinetics. Considerable degradation is observed of protein fragments that remain on their substrate surface after plasma treatment.

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“…The emission spectra from the plasma plumes using various working gases clearly indicate the excited NO, O, OH, N 2 , and N 2 + . 2,[29][30][31][32] Since the critical radicals to cell death are O, NO, and OH radicals, the richness of these species may make the plasma jets suitable for biomedical applications. [33][34][35] The excitation temperatures of He or Ar lines were measured by using the Boltzmann plot -method.…”

Section: B Optical Characteristicsmentioning

confidence: 99%

Comparison of the characteristics of atmospheric pressure plasma jets using different working gases and applications to plasma-cancer cell interactions

et al. 2013

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Atmospheric pressure plasma jets employing nitrogen, helium, or argon gases driven by low-frequency (several tens of kilohertz) ac voltage and pulsed dc voltage were fabricated and characterized. The changes in discharge current, optical emission intensities from reactive radicals, gas temperature, and plume length of plasma jets with the control parameters were measured and compared. The control parameters include applied voltage, working gas, and gas flow rate. As an application to plasma-cancer cell interactions, the effects of atmospheric pressure plasma jet on the morphology and intracellular reactive oxygen species (ROS) level of human lung adenocarcinoma cell (A549) and human bladder cancer cell (EJ) were explored. The experimental results show that the plasma can effectively control the intracellular concentrations of ROS. Although there exist slight differences in the production of ROS, helium, argon, or nitrogen plasma jets are found to be useful in enhancing the intracellular ROS concentrations in cancer cells

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Room-temperature atmospheric pressure plasma plume for biomedical applications

Abstract: Articles you may be interested in Cold atmospheric pressure plasma jets as sources of singlet delta oxygen for biomedical applications

Cited by 606 publications

References 6 publications

A hypersonic plasma bullet train traveling in an atmospheric dielectric-barrier discharge jet

A hypersonic plasma bullet train traveling in an atmospheric dielectric-barrier discharge jet

Protein destruction by atmospheric pressure glow discharges

Comparison of the characteristics of atmospheric pressure plasma jets using different working gases and applications to plasma-cancer cell interactions

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