Role of the NH2, OH and As = As Groups in Parasitotoxic Action of Arsphenamine Derivatives

Inhibition of the respiration of Trypanosoma rhodesiense by thiols

“…Our results show that the respiration of T. rhodesiense is markedly inhibited by low concentrations of hydrogen peroxide comparable with those detected during oxidation of the thiols. Reiner & Leonard (1932) and Strangeways (1937) found that peroxide also affects the motility of T. equiperdurn.…”