Role of Synovial Fluid Cells in the Healing of Flexor Tendons

Menon, Jayasanker; Frykman, Gary K.; Swarm, Orval J.

doi:10.1097/00003086-198510000-00043

Cited by 5 publications

(2 citation statements)

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“…Menon et al 16 found that free irradiated flexor tendons were able to heal in the rabbit knee model, and they attributed this to synovial nutrition and cellular ingrowth. In a rabbit study, Fulkerson et a1.12 found that free-floating patellar tendon grafts could remain metabolically active without vascular ingrowth up to 2 years after implantation into the suprapatellar pouch.…”

Section: Discussionmentioning

confidence: 99%

Arthroscopic and histologic analysis of human patellar tendon autografts used for anterior cruciate ligament reconstruction

et al. 1993

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To evaluate the fate of patellar tendon autografts in humans, the knees of 23 patients who had undergone anterior cruciate ligament reconstruction were examined 3 weeks to 6.5 years postoperatively. Arthroscopy and biopsy were performed on all patients. The patellar tendon autografts progressed through four stages of ligamentization after reconstruction. The first stage of repopulation occurred during the first 2 months and was evidenced by a viable 3-week specimen with an increasing fibroblast number and active nuclear morphology. Over the next 10 months, the graft went through a stage of rapid remodeling in which the fibroblast count increased markedly, the active nuclear morphology and neovascularity remained increased, and more areas of degeneration were present as the percentage of mature collagen decreased. The third stage or "maturation" stage occurred over the next 2 years and was characterized by a slow decline in the nuclei and the maturation of the collagen matrix. By 3 years the grafts were ligamentous by all histologic criteria examined. The authors conclude that human autogenous patellar tendon grafts are viable as early as 3 weeks postoperatively and may not go through a necrotic stage. They then progress through a prolonged process of ligamentization that takes as long as 3 years to complete.

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Section: Discussionmentioning

confidence: 99%

Arthroscopic and histologic analysis of human patellar tendon autografts used for anterior cruciate ligament reconstruction

et al. 1993

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“…Phospholipid was shown to reduce peritoneal adhesions by 80% following surgery in rabbits (Bhandarkar et al 1999). An important fi nding by Menon et al (1985) was that non-viable tendon can be healed when placed in a synovial cavity, directly implying a role of synovial fl uid in tendon repair. The potential for using SAPL therapy in tendon injuries extends beyond merely lubricating the damaged surfaces of tendon and tendon sheath.…”

Section: Discussionmentioning

confidence: 99%

Surface-active phospholipid (surfactant) in equine tendon and tendon sheath fluid

Mills

Hills

2005

New Zealand Veterinary Journal

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Effect of hyaluronic acid/chondroitin sulfate on healing of full‐thickness tendon lacerations in rabbits

Meyers

Seaber

Glisson

et al. 1989

Journal Orthopaedic Research

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Viscoat, a high-molecular-weight, highly purified hyaluronic acid (HA) and chondroitin sulfate (CS) compound, was instilled around rabbit plantaris tendon following full-thickness laceration and surgical repair. After 3 weeks of immobilization, no significant difference in adhesion strength or tensile strength of the healing tendons existed between Viscoat-treated tendons and controls. This contradicts previous studies which suggest that hyaluronic acid reduces postoperative tendon adhesions. Further studies examining tendon adhesions after less severe degrees of tendon injury and using direct, quantitative measurement techniques are warranted to demonstrate whether HA has a beneficial effect on tendon healing.

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Role of Synovial Fluid Cells in the Healing of Flexor Tendons

Cited by 5 publications

References 0 publications

Arthroscopic and histologic analysis of human patellar tendon autografts used for anterior cruciate ligament reconstruction

Arthroscopic and histologic analysis of human patellar tendon autografts used for anterior cruciate ligament reconstruction

Surface-active phospholipid (surfactant) in equine tendon and tendon sheath fluid

Effect of hyaluronic acid/chondroitin sulfate on healing of full‐thickness tendon lacerations in rabbits

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