Role of Shortened QTc Dispersion in In-hospital Cardiac Events in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome

Lai, Chi Cheng; Hsiao, Hsiang Chiang; Hsiao, Shin Hung; Huang, Wei; Chiou, Chuen Wang; Yeh, Tung Cheng; Hwang, Hwong Ru; Lee, Doyal; Mar, Guang Yuan; Lin, Shih Kai; Chiou, Kuan Rau; Lin, Szu‐Ting; Liu, Chun Peng

doi:10.1016/s1726-4901(09)70262-x

Cited by 4 publications

(2 citation statements)

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“…However, few studies focused on the relationship between Hcy and the QTc interval in the general population. Detection of the QTc interval can help predict the risk of cardiovascular disease (CVD) events [16–19]. Therefore, in this study, we evaluated plasma Hcy levels and the QTc interval in a general population to determine whether there is an association between Hcy levels and the QT interval.…”

Section: Introductionmentioning

confidence: 99%

Plasma homocysteine levels associated with a corrected QT interval

Guo

Sun

et al. 2017

BMC Cardiovasc Disord

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BackgroundLittle is known about the relationship between homocysteine (Hcy) levels and the QT interval. We examined the association of different Hcy levels with corrected QT (QTc) intervals in a general population.MethodsPlasma levels of Hcy were assessed in a population-based study of 7002 participants 35 years of age and older from 2012 to 2013. Twelve-lead ECGs were performed on all participants and analyzed automatically.ResultsThe distribution of Hcy levels was determined for an entire population after the data were grouped into quartiles (Q1: <=11.1umol/L; Q2: 11.1–13.8umol/L; Q3: 13.8–18.2 umol/L; Q4 > 18.2 umol/L). The mean value of the QTc interval in each quartile was 433.2 ± 23.8 ms, 430.0 ± 24.6 ms, 429.2 ± 24.5 ms and 430.6 ± 25.7 ms. Multiple logistic regression analyses showed that, compared with the second quartile, and after fully adjusting for potential confounding factors, the odds for QTc > 440 ms in the first and fourth quartile increased (P < 0.05), (OR: 1.23, 95% CI: 1.05–1.43 for Q1; OR: 1.40, 95% CI: 1.19–1.65 for Q4).ConclusionsQTc interval was associated with the Hcy level in this general population.Electronic supplementary materialThe online version of this article (doi:10.1186/s12872-017-0617-z) contains supplementary material, which is available to authorized users.

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Section: Introductionmentioning

confidence: 99%

Plasma homocysteine levels associated with a corrected QT interval

Guo

Sun

et al. 2017

BMC Cardiovasc Disord

View full text Add to dashboard Cite

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“…1,2 The fact that clinically manifest CAD in the young adult is relatively uncommon implies that these patients are atypical of the general population. [3][4][5][6][7][8] Cigarette smoking has been shown to be the single factor most strongly associated with CAD in young adults. 9 Kannel et al found that in patients included in the Framingham…”

Section: Introductionmentioning

confidence: 99%