Role of short-term follow-up magnetic resonance imaging in the detection of post-operative residual breast cancer

Abstract

The aim of the present study was to evaluate the role of short-term follow-up magnetic resonance imaging (MRI) in the detection of postoperative residual breast cancer. A retrospective analysis was performed on 10 patients who were diagnosed with non-malignant breast lesions by preoperative clinical, ultrasound and mammography examinations and intraoperative frozen-section pathology. These patients were finally confirmed as having malignant breast lesions by paraffin-embedded tissue histology and corresponding received second surgeries. Routine MRI, enhancement MRI and echo-planar imaging-diffusion-weighted imaging were performed on the 10 patients within 1 month after the first surgery. All the cases showed a local distortion of mammary architecture revealed by routine MRI and enhancement MRI images. The enhancement characteristics of the 10 cases were as follows: 3 cases featured stippled enhancement, 2 had small nodular enhancement, 1 showed dendritic enhancement, 1 had a ring-shaped enhancement of the cystic wall and 3 had no abnormal enhancement. The lesions of 7 cases had a type-I enhancement curve (progressive enhancement pattern) and 3 cases had a type-II curve (plateau pattern). The lesions of 4 cases had a decreased apparent diffusion coefficient. In total, 4 cases of tumor residue were diagnosed by MRI and the second pathological examination, while in 1 case the tumor residue was misdiagnosed by MRI but confirmed by the second pathological examination. In conclusion, the present study suggested that short-term follow-up MRI may be of value in the diagnosis of postoperative residual breast tumors and may be helpful for surgeons to develop an accurate surgical plan.

Maintenance of body weight is an important determinant for the risk of ischemic stroke: A nationwide population-based cohort study

“…In a study that assessed CVD-related prognoses due to differences in the mechanism of weight loss, it was found that the effects of intentional and unintentional weight loss might be different [19]. Intentional weight reduction, such as decreasing calorie intake and increasing physical activity, had a positive effect on CVD risk, and the benefit increased with increased weight loss, especially in obese Caucasian women [7,20,21]. Nevertheless, whether intentional or unintentional, weight loss had a negative effect on the CVD outcome in older Caucasian men [22].…”

“…In our study, the weight loss group contained a higher proportion of elderly subjects as well as underlying diseases associated with frailty, such as ischemic heart disease, chronic obstructive pulmonary disease, and chronic kidney disease. In a study by Look AHEAD researchers, two-thirds of participants with a moderate to large intentional weight loss (more than 3%) showed a partial or whole weight regain [21]. It was reported that weight regain after diet-induced intentional weight loss weakened any cardiovascular benefits obtained by weight loss [27].…”

Mastectomy Flap Thickness and Complications in Nipple-Sparing Mastectomy: Objective Evaluation using Magnetic Resonance Imaging

“… 49 , 50 Postoperative MRI after surgical management of breast cancer is less commonly utilized in infrequent cases of potential residual breast tissue or in the work-up of palpable masses. 51 , 52 …”