“…Due to the complicated morphology of multiple ASDs, importance of real-time 3D TEE during this procedure should be highlighted. Recently, several studies have proved the advantage of real-time 3D TEE and realized the invaluable role of this new method in preoperative assessment, intraoperative guidance, as well as postoperative evaluation during intervention procedure [16][17][18][19]. Successful closure of ASD is dependent on accurate assessment of ASD size, rim architecture, and relationship of the defect to adjacent cardiac structures.…”