Role of polyethyleneimine (PEI) in synthesis of zinc oxide nanoparticles and their cytotoxicity effects

Alavi, Seyed Jamal; Khalili, Niloofar; Oskuee, Reza Kazemi; Verma, K.D.; Darroudi, Majid

doi:10.1016/j.ceramint.2015.04.129

Cited by 8 publications

(4 citation statements)

References 26 publications

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“…In contrast, Abbasi et al 62 showed that the biosynthesized ZnO NPs displayed a maximum cytotoxic effect on hepatocellular carcinoma (HepG2) human cells at a lower concentration of 100 µg/mL. Nevertheless, our results revealed that the IC 50 value was more than 50 µg/mL compared to those chemically synthesized ZnO NPs 34,63,64 ; hence, considered as biocompatible to the cell line.…”

Section: Ftir Analysis the Bioactive Molecules Composition Of Cfs Ancontrasting

confidence: 83%

Biosynthesis of zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its antibacterial and biocompatibility properties

Rahman

Mohamad

Zaidan

et al. 2020

Sci Rep

113

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This study aims to utilize the cell-biomass (CB) and supernatant (CFS) of zinc-tolerant Lactobacillus plantarum TA4 as a prospective nanofactory to synthesize ZnO NPs. The surface plasmon resonance for the biosynthesized ZnO NPs-CFS and ZnO NPs-CB was 349 nm and 351 nm, respectively, thereby confirming the formation of ZnO NPs. The FTIR analysis revealed the presence of proteins, carboxyl, and hydroxyl groups on the surfaces of both the biosynthesized ZnO NPs that act as reducing and stabilizing agents. The DLS analysis revealed that the poly-dispersity indexes was less than 0.4 for both ZnO NPs. In addition, the HR-TEM micrographs of the biosynthesized ZnO NPs revealed a flower-like pattern for ZnO NPs-CFS and an irregular shape for ZnO NPs-CB with particles size of 291.1 and 191.8 nm, respectively. In this study, the biosynthesized ZnO NPs exhibited antibacterial activity against pathogenic bacteria in a concentration-dependent manner and showed biocompatibility with the Vero cell line at specific concentrations. Overall, CFS and CB of L. plantarum TA4 can potentially be used as a nanofactory for the biological synthesis of ZnO NPs.

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Section: Ftir Analysis the Bioactive Molecules Composition Of Cfs Ancontrasting

confidence: 83%

Biosynthesis of zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its antibacterial and biocompatibility properties

Rahman

Mohamad

Zaidan

et al. 2020

Sci Rep

113

View full text Add to dashboard Cite

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“…On the other hand, the urchin-like morphology of ZnO (NU) forms through a modified reaction of ZnO NF using PEI as stabilizing/capping agent. 46 The same as NF, this morphology forms as bunches of nanowires but smaller and thinner due to the presence of PEI. It has been reported that the addition of PEI influences the density of nanowires owing to the alteration in the nucleation process of the ZnO seed layer.…”

Section: Resultsmentioning

confidence: 87%

“…The synthesis process in a slightly acidic medium (pH 5.4) results in small nanoparticles of ZnO forming sponge-like morphology, and it is observed that the morphology remains unchanged during annealing. On the other hand, the urchin-like morphology of ZnO (NU) forms through a modified reaction of ZnO NF using PEI as stabilizing/capping agent . The same as NF, this morphology forms as bunches of nanowires but smaller and thinner due to the presence of PEI.…”

Section: Resultsmentioning

confidence: 99%

Impact on the Photocatalytic Dye Degradation of Morphology and Annealing-Induced Defects in Zinc Oxide Nanostructures

et al. 2023

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In this study, three different morphologies, nanoflower (NF), nano sponge (NS), and nano urchin (NU), of zinc oxide (ZnO) nanostructures were synthesized successfully via a mild hydrothermal method. After synthesis, the samples were annealed in the atmosphere at 300, 600, and 800 °C. Although annealing provides different degradation kinetics for different morphologies, ZnO NS performed significantly better than other morphologies for all annealing temperatures we used in the study. When the photoluminescence, electron paramagnetic resonance spectroscopy, BET surface, and X-ray diffraction analysis results are examined, it is revealed that the defect structure, pore diameter, and crystallinity cumulatively affect the photocatalytic activity of ZnO nanocatalysts. As a result, to obtain high photocatalytic activity in rhodamine B (RhB) degradation, it is necessary to develop a ZnO catalyst with fewer core defects, more oxygen vacancies, near band emission, large crystallite size, and large pore diameter. The ZnO NS-800 °C nanocatalyst studied here had a 35.6 × 10–3 min–1 rate constant and excellent stability after a 5-cycle photocatalytic degradation of RhB.

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“…Nanoparticles, because of their small size and unique optical, biological, and chemical properties possess wide application in biotechnology and medicine [4][5][6]. Quantum dots (QDs) are an example of this type.…”

Section: Introductionmentioning

confidence: 99%

Mn‐doped ZnS quantum dots‐chlorin e6 shows potential as a treatment for chondrosarcoma: an in vitro study

Mohsenian

Shanei

Alavi

et al. 2019

IET nanobiotechnol.

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Chondrosarcoma is the second-most malignant cancer of the bone and routine treatments such as chemotherapy and radiotherapy have not responded to the treatment of this cancer. Due to the resistance of chondrosarcoma to radiotherapy, the combination of therapeutic methods has been considered in recent years. In this study, a novel combination approach is used that allows photodynamic therapy to be activated by X-rays. The synthesis of Mn-doped zinc sulphide (ZnS) quantum dots was carried out and chlorin e6 photosensitiser attached by covalent and non-covalent methods and their application as an intracellular light source for photodynamic activation was investigated. The toxicity of each nanoparticles was evaluated on chondrosarcoma cancer cells (SW1353) before and after radiation. Also, the effect nanoparticle-photosensitiser conjugated type was investigated in the therapeutic efficacy. The characterisation test (SEM, TEM, EDS, TGA, XRD and ICP analyses) was shown successful synthesis of Mn-doped ZnS quantum dots. Chondrosarcoma cancer cell viability was significantly reduced when cells were treated with MPA-capped Mn-doped ZnS quantum dots-chlorin e6 with spermine linker and with covalent attachment (P ≤ 0.001). These results indicate that X-ray can activate the quantum dot complexes for cancer treatment, which can be a novel method for treatment of chondrosarcoma.

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Role of polyethyleneimine (PEI) in synthesis of zinc oxide nanoparticles and their cytotoxicity effects

Cited by 8 publications

References 26 publications

Biosynthesis of zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its antibacterial and biocompatibility properties

Biosynthesis of zinc oxide nanoparticles by cell-biomass and supernatant of Lactobacillus plantarum TA4 and its antibacterial and biocompatibility properties

Impact on the Photocatalytic Dye Degradation of Morphology and Annealing-Induced Defects in Zinc Oxide Nanostructures

Mn‐doped ZnS quantum dots‐chlorin e6 shows potential as a treatment for chondrosarcoma: an in vitro study

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