Role of physical and chemical interactions in the antibacterial behavior of ZnO nanoparticles against E. coli

Jiang, Yunhong; Zhang, Lingling; Wen, Dongsheng; Ding, Yulong

doi:10.1016/j.msec.2016.08.044

Cited by 132 publications

(74 citation statements)

References 44 publications

(51 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ZnO NP antibacterial activity may associate with the accretion in bacterial cells cytoplasm and promote the release of Zn 2+ . It leads to the fragmentation of bacterial cell membrane, damage in membrane protein and genomic weakness resulting in the death of bacteria [27][28][29]. Fig.…”

Section: Characterization Of Zinc Oxide Nanoparticlesmentioning

confidence: 99%

In Vitro Analysis: The Antimicrobial and Antioxidant Activity of Zinc Oxide Nanoparticles From Curcuma Longa

Jacob

Periakaruppan

2019

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: Curcuma longa is a known natural medicine for inflammation from ancient times. It has a low absorption rate and poor solubility. Hence, it is used for the green synthesis of nanoparticles. Zinc oxide nanoparticle (ZnO NPs) is famous nanoparticles which are economical, less toxic, and brilliantly biocompatible. They have potential biomedical properties, mainly anticancer, antidiabetic, and antimicrobial.Methods: The present study was designed to investigate in vitro analysis of the antimicrobial activity against pathogenic bacteria and fungi and its ability to scavenge reactive oxygen radicals of ZnO NPs.Results and Conclusion: The results indicated that ZnO NPs produced from C. longa had higher antimicrobial activity against Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes, and Candida albicans. Therefore, we suggest that ZnO NPs can be used as the antimicrobial agent. It is a good scavenger of superoxide radical, nitric oxide, and hydrogen peroxide and has reducing power, which is greater than ascorbic acid at a higher concentration.

show abstract

Section: Characterization Of Zinc Oxide Nanoparticlesmentioning

confidence: 99%

In Vitro Analysis: The Antimicrobial and Antioxidant Activity of Zinc Oxide Nanoparticles From Curcuma Longa

Jacob

Periakaruppan

2019

Asian J Pharm Clin Res

View full text Add to dashboard Cite

show abstract

“…They have been widely used in a wide range of applications in different areas, such as industry (rubber, concrete [7], and textile [8]) and biological applications (anti-bacterial, antiinflammatory etc. [9]). ZnO NPs appear in different forms, including nano-rods [10] and nanospheres [11].…”

Section: Introductionmentioning

confidence: 99%

Influence of ZnO Nanoparticles on Candida albicans of Human Male Pleural Fluid

Katafa

Hamid

2020

eijs

View full text Add to dashboard Cite

The utilization of metal oxide nanoparticles, especially zinc oxide, is of a great importance in the medical field because of its physical and chemical properties as well as its antimicrobial potential effects. In our study, the ZnO nanoparticles were synthesized by the precipitation method where pH=14. ZnO nanoparticles were characterized by ultraviolet-visible spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM) and atomic force microscope (AFM). Antifungal activity of the ZnO was tested against candida albicans. The results showed that C. albicans (15 samples) became resistant to the fungal activity after testing its sensitivity to several types of fungal antibiotics. UV-vis spectroscopy, XRD, TEM and AFM showed that this precipitation synthetic method can produce a good quality of ZnO nanoparticles with sizes in the range of nanometer scale. In ZnO NPs (calcined), the inhibition zone diameter of C. albicans was 11 mm at a ZnO NPs concentration of 800 mg/ml, while no inhibition zones were formed at the other concentrations (0.25, 0.5, 1, 2, 10, 50 and 500 mg/ml). Using ZnO NPs (not calcined), the inhibition zone diameter of C. albicans was 24 mm at a concentration of 800 mg/ml, while no inhibition zones were observed at the other concentrations (0.25, 0.5, 1, 2, 10, 50 and 500 mg/ml). In addition, a toxicity test was performed on mice and proved that ZnO NPs are effective against C. albicans with a toxic effect on liver and spleen cells in rats. The aim of this research was to characterize the in vitro activity of ZnO nanoparticles synthesized by the precipitation method against C. albicans of human male pleural fluid using the well diffusion method as well as their toxic effects on both liver and spleen cells in mice.

show abstract

“…Besides, ZnO particles are effective for inhibiting both Gram positive and Gramnegative bacteria. They also show antibacterial property for spores that are high-temperature resistant and high-pressure resistant [10].…”

Section: Introductionmentioning

confidence: 99%

Facile Synthesis of ZnO-Cu2O Composite Nanoparticles and Effect of Cu2O Doping in ZnO on Antimicrobial Activity

Bayahia¹,

M²,

Hassan³

et al. 2017

Mod Chem Appl

View full text Add to dashboard Cite

The comparative antibacterial activity of ZnO and ZnO-Cu 2 O composite nanoparticles has been investigated and presented in this manuscript. The present study describes the facile synthesis of pristine ZnO nanoparticles and ZnO-Cu 2 O composite nanoparticles respectively. ZnO nanoparticles and ZnO-Cu 2 O composite nanoparticles have been synthesized by simple solution process using zinc nitrate hexahydrate and copper acetate as sole precursor. The diameter of each ZnO and ZnO-Cu 2 O composite nanoparticles lies between 200 to 600 nm respectively as observed from SEM images. Herein, we scrutinized the influence of Cu 2 O doping in ZnO on the antibacterial activity. The E. coli bacteria which are generally ever-present have been chosen as the model organisms for relative study. The experimental procedures for the antibacterial test include spectroscopic method, taking different concentrations (10-40 μg/ml) of samples to unearth the minimum inhibitory concentration. Our analysis says that the minimum concentration of ZnO and ZnO-Cu 2 O composite nanoparticles which inhibited the growth of E. coli bacteria was found to be 10 μg. A mechanism was also proposed to describe the better antibacterial activity of the ZnO-Cu 2 O composite nanoparticles than the pure ZnO nanoparticles.

show abstract

Role of physical and chemical interactions in the antibacterial behavior of ZnO nanoparticles against E. coli

Abstract: ABSTRACT:Zinc oxide (ZnO) nanoparticles (NPs) exhibit antibacterial activity against both Gram-positive and Gram-negative bacteria. However, the antimicrobial mechanism of ZnO NPs remains unclear. In this study, we investigated the interactions among ZnO NPs, released chemicals (Zn

Cited by 132 publications

References 44 publications

In Vitro Analysis: The Antimicrobial and Antioxidant Activity of Zinc Oxide Nanoparticles From Curcuma Longa

In Vitro Analysis: The Antimicrobial and Antioxidant Activity of Zinc Oxide Nanoparticles From Curcuma Longa

Influence of ZnO Nanoparticles on Candida albicans of Human Male Pleural Fluid

Facile Synthesis of ZnO-Cu2O Composite Nanoparticles and Effect of Cu2O Doping in ZnO on Antimicrobial Activity

Contact Info

Product

Resources

About