“…Dietary fish oil has been demonstrated to: protect mice against infection with numerous extracellular bacterial pathogens, regulate serum triglycerides and cholesterol levels, inhibit synthesis of lipid mediators of inflammation (PGE 2 , arachidonic acid, cyclo-oxygenase, 5-lipoxygenase), alter cellular functions of polymorphonuclear leukocytes, modulate lymphocyte proliferation and cytokine production, and increase endogenous host anti-oxidant capacity, e.g., SOD and catalase (Alam et al, 1991;Blok et al, 1992;Fernandes and Venkataraman, 1993). These effects have been proposed to account for the potent anti-inflammatory properties of omega (ω)-3 fatty acids (FA) in human, non-human primate, and rodent disease models.…”