Role of irritable bowel syndrome in subjective lactose intolerance

Vesa, Tuula; Seppo, L; Marteau, P.; Sahi, Timo; Korpela, Riitta

doi:10.1093/ajcn/67.4.710

Cited by 117 publications

(79 citation statements)

References 32 publications

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“…The common belief among IBS patients is that lactose is the main cause of their symptoms (42). This may be the cause for the lower consumption of milk and milk products found among the unguided IBS patients in this study, which in turn explains the observation made here of a lower intake of calcium in these patients.…”

Section: Discussionsupporting

confidence: 59%

Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome

Østgaard

Hausken

Gundersen³

et al. 2012

Mol Med Report

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Abstract. The present study investigated the diet and quality of life of irritable bowel syndrome (IBS) patients in comparison to the background population. Furthermore, it studied the effects of guidance on diet management on changes in food intake, quality of life and symptoms. A total of 35 healthy controls, 36 IBS patients and 43 IBS patients who had received guidance on diet management 2 years earlier were included. The controls and patients were asked to complete an FFQ questionnaire, an SF-NDI questionnaire, an IBS-QoL questionnaire and a Birmingham IBS symptom score questionnaire. There were no statistical differences in the intake of calories, carbohydrates, proteins and fat between the controls and IBS patients, with or without guidance on diet management. IBS patients made a conscious choice to avoid certain food items, some of which belong to fermentable oligosaccharides, disaccharides, monosacharides and polyols (FODMAPs). They had a higher consumption, however, of other food items that are rich in FODMAPs. They also avoided other food sources which are crucial for their health. Two years after receiving guidance on diet management, IBS patients had a different diet profile. They avoided all FODMAP-rich food, consumed more food with probiotic supplements and did not avoid food sources that were crucial to their health. In addition, they had improved quality of life and reduced symptoms. Although at first sight the diet of IBS patients did not differ from that of the background population, detailed examination showed avoidance of certain food items. Guidance on the management of diet improved their choice of a healthier diet, improved quality of life and reduced IBS symptoms. IntroductionIrritable bowel syndrome (IBS) is a chronic gastrointestinal disorder in absence of any structural, physiological or biochemical abnormalities in the gastrointestinal tract (1). The condition is classified as a functional disorder for which the diagnosis is based on the presentation of symptoms. These symptoms are abdominal discomfort or pain, bloating and abdominal distension, and changes in bowel habit between diarrhoea and constipation (1). The degree of symptoms varies in different patients from tolerable to severe, where the experience of pain may vary from a nagging, colicky, sharp or dull feeling of pain. Also, the time pattern and discomfort varies immensely from patient to patient (2-14). Some complain of daily symptoms, while others report intermittent pain at intervals of weeks/months. The supportive symptoms mentioned above may also be used to subclassify IBS patients into three subtypes: diarrhoea-predominant (IBS-D), constipationpredominant (IBS-C) and alternating constipation/diarrhea (IBS-M) (2-4).The estimated prevalence of IBS varies from 12 to 30%; this large variation is explained by the use of different definitions in different studies (15). A cross-sectional population-based survey conducted in Oppland and Hedmark County in Norway using recent diagnostic criteria estimated the prevalence to affe...

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Section: Discussionsupporting

confidence: 59%

Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome

Østgaard

Hausken

Gundersen³

et al. 2012

Mol Med Report

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“…This is in line with other studies [6,8,9] showing that not all individuals with lactose malabsorption report symptoms from food containing lactose. T he colonic micro biota is variable [28] and the individual sensitivity to feel distension of the colon and to sense discomfort varies [29] . Accordingly, the recognition of the possible link between milk consumption and abdominal symptoms is not always easy [30] .…”

Section: Discussionmentioning

confidence: 99%

Molecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms

Anthoni¹

2007

WJG

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“…The common believe among IBS patients is that lactose is the main cause of their symptoms (39). They have a lower consumption of milk and milk products (38).…”

Section: Diet In Ibs Patientsmentioning

confidence: 99%

The role of diet in the pathogenesis and management of irritable bowel syndrome (Review)

El‐Salhy

Østgaard

Gundersen³

et al. 2012

Int J Mol Med

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Abstract. Most patients with irritable bowel syndrome (IBS) believe that diet plays a significant role in inducing IBS symptoms and desire to know what foods to avoid. It has been found that the intake of calories, carbohydrates, proteins and fat by IBS patients does not differ from that of the background population. IBS patients were found to avoid certain food items that are rich in fermentable oligo-, di-and monosacharides and polyols (FODMAPs), but they did have a high consumption of many other FODMAP-rich food items. The diet of IBS patients was found to consist of a low calcium, magnesium, phosphorus, vitamin B2 and vitamin A content. There is no consistent evidence that IBS patients suffer from food allergy, nor is there documented evidence that food intolerance plays a role in IBS symptoms. Abnormalities in gut hormones have been reported in IBS patients. As gut hormones control and regulate gastrointestinal motility and sensation, this may explain the abnormal gastrointestinal motility and visceral hypersensitivity reported in these patients. Guidance concerning food management which includes individually based restrictions of FODMAP-rich food items and individual evaluation of the effects of protein-, fat-and carbohydrate-rich/poor diets may reduce IBS symptoms.

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Role of irritable bowel syndrome in subjective lactose intolerance

Cited by 117 publications

References 32 publications

Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome

Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome

Molecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms

The role of diet in the pathogenesis and management of irritable bowel syndrome (Review)

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