2017
DOI: 10.1111/sji.12617
|View full text |Cite
|
Sign up to set email alerts
|

Role of Intracystic Cytokines and Nitric Oxide in Ovarian Neoplasms

Abstract: The development of new biomarkers for the diagnosis and prognosis of ovarian cancer may provide an opportunity for new therapies. In this study, we aimed to compare cytokines (interleukin [IL]-2, IL-5, IL-6, IL-8, IL-10 and tumour necrosis factor [TNF]-α) and nitric oxide (NO) metabolite levels in non-neoplastic tumours, benign primary ovarian tumours and malignant primary ovarian neoplasms. The secondary aim was to relate cytokine and intracystic NO metabolite levels to clinical, laboratory and pathologic cha… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
7
0

Year Published

2019
2019
2024
2024

Publication Types

Select...
10

Relationship

0
10

Authors

Journals

citations
Cited by 10 publications
(7 citation statements)
references
References 54 publications
(57 reference statements)
0
7
0
Order By: Relevance
“…Several biological processes and pathways correlated with the tumorigenesis and progression of ccRCC were identified including "cytokine-cytokine receptor interaction, " "cell adhesion molecules (CAMs), " "complement and coagulation cascades, " "leukocyte migration, " "regulation of leukocyte activation, " "regulation of immune effector process, " and so on. It was known that the expression or function of cytokines, including cellular self-renewal, senescence, migration, and apoptosis was often altered in tumor tissues compared with healthy tissues (52)(53)(54). CAMs was found to promote the metastasis of head and neck squamous cell carcinoma via detaching the tumor cells from primary tumor and decreasing the intercellular adhesion (55).…”
Section: Discussionmentioning
confidence: 99%
“…Several biological processes and pathways correlated with the tumorigenesis and progression of ccRCC were identified including "cytokine-cytokine receptor interaction, " "cell adhesion molecules (CAMs), " "complement and coagulation cascades, " "leukocyte migration, " "regulation of leukocyte activation, " "regulation of immune effector process, " and so on. It was known that the expression or function of cytokines, including cellular self-renewal, senescence, migration, and apoptosis was often altered in tumor tissues compared with healthy tissues (52)(53)(54). CAMs was found to promote the metastasis of head and neck squamous cell carcinoma via detaching the tumor cells from primary tumor and decreasing the intercellular adhesion (55).…”
Section: Discussionmentioning
confidence: 99%
“…All selected articles passed the STROBE checklist criteria (Supplementary Table S2). These include the articles of Sanna et al [35], Micheli et al [36], de Lima et al [37], Rodrigues et al [38], Kampan et al [25], Wertel et al [39], Zhang et al [40], Crispim et al [41], Shi et al [42], Li et al [43], Dalal et al [44], Han et al [45], Kumar et al [46], Martins-Filho et al [47], Cantón-Romeo et al [48], Sanguinette et al [49], Hao et al [50], Mikuła-Pietrasik et al [51], Chudecka-Głaz et al [ S1 and S2).…”
Section: Strobe Checklistmentioning
confidence: 99%
“…But as suggested above, the actions of NO on cancer biology is biphasic and it can be proposed that the inherent nature of tumor-driven NO dominantly propagates cancer growth. In ovarian neoplasias, cyst fluid of malignant tumors contains higher levels of NO in comparison to benign lesions (Martins-Filho et al 2017). In patients with oral precancerous and cancerous lesions, nitrite (NO 2 ) and nitrate (NO 3 ) plasma levels are higher than healthy controls (Patel et al 2009).…”
Section: Resultsmentioning
confidence: 99%