Role of inhibition in language switching: Evidence from event-related brain potentials in overt picture naming

Electrophysiological evidence that inhibition supports lexical selection in picture naming

“…They concluded that their data confirmed the role of inhibition in reducing semantic interference during picture naming. It should be noted, however, that other investigators (e.g., De Bruin et al, 2014;Forstmann et al, 2008;Verhoef et al, 2009) have associated inhibition with right inferior frontal cortex rather than with orbitomedial prefrontal cortex, as de Zubicaray et al did.…”

“…For example, bilingual speakers have been shown to use inhibition to suppress a non-target language (e.g., De Bruin et al, 2014;Guo et al, 2011;Misra et al, 2012;Jackson et al, 2001;Roelofs et al, 2011;Verhoef et al, 2009). There is also evidence suggesting that inhibition deficits contribute to the impaired speech production of children with specific language impairment (SLI; e.g., Henry et al, 2012;Im-Bolter et al, 2006;Seiger-Gardner and Schwartz, 2008;Spaulding, 2010).…”

“…The component of central interest to the present study is the N2, a negative going ERP component that occurs between 200 and 400 ms after stimulus onset. Although there are various forms of the N2 that can be elicited in different tasks (see Folstein and Van Petten, 2008, for review), of particular interest in the current study is the N2 elicited in tasks requiring response inhibition, which has a frontal-central to right-frontal scalp distribution, and has been associated with activity in the medial prefrontal and right inferior frontal cortices (e.g., Forstmann et al, 2008;Van den Wildenberg et al, 2011;Verhoef et al, 2009). For instance, in the go/no-go task, a larger N2 is typically found on no-go relative to go trials, suggesting that the N2 reflects the successful inhibition of the response (e.g., Bruin et al, 2001;Carriero et al, 2007;Dong et al, 2009;Eimer, 1993;Falkenstein et al, 1999;Kok, 1986).…”

“…Although modulations of the N2 are mostly examined in non-linguistic studies, they have also been found in psycholinguistic studies (e.g., Verhoef et al, 2009). Costa et al (2009) used the continuous semantic blocking paradigm and found that the mean amplitude of an N2 increased with the ordinal position of the pictures in the experiment, indicating that word retrieval became increasingly difficult as more items from the same semantic category were activated in memory.…”

Event-Related Brain Potentials in the Study of Inhibition: Cognitive Control, Source Localization and Age-Related Modulations

“…Recently, there has been an increasing interest in inhibition, which has specifically focused on the neural underpinnings of inhibitory processes and the role of inhibition in cognitive domains, such as memory, language and attention (Verhoef et al 2009;Neuhaus et al 2010;Yi and Friedman 2011;Albert et al 2013). Several of these studies have examined the relevance of inhibitory processes in normal aging (Mayas et al 2012;Turner and Spreng 2012;Haring et al 2013;Wostmann et al 2013), as well as a variety of clinical conditions, such as Alzheimer's disease (AD; Collette et al 2009; C. Thomas et al 2010;Cheng et al 2012), mild cognitive impairment (MCI; Belleville et al 2007), traumatic brain injury (TBI; Dimoska-Di Marco et al 2011), depression (Dai and Feng 2011;Bobb et al 2012), anxiety (Robinson et al 2013), schizophrenia (Hughes et al 2012), fibromyalgia (Mercado et al 2013), attention deficithyperactivity disorder (ADHD; Senderecka et al 2012), alcoholism (Padilla et al 2011) and psychopathy (Verona et al 2012).…”