Role of image-guided core-needle biopsy in the management of patients with lymphoma.

Abstract

At St Bartholomew's Hospital (SBH), image-guided core-needle biopsy has proven to be a quick, safe, and efficient alternative to excisional biopsy in the evaluation of lymphoproliferative disorders at presentation, recurrence, or progression. It should become the procedure of choice for histologic sampling in the absence of peripheral lymphadenopathy.

Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC)

“…Since excisional lymph node biopsies put the patient at risk for sepsis, especially in erythrodermic patients whose skin is often colonized with Staphylococcus, alternative methods to obtain nodal tissue (core biopsy or fine needle aspiration [FNA]) have been suggested as potential substitutes particularly if combined with flow cytometry. 70 However, these alternate methods may have inadequate or poorly representative sampling 71 or incomplete concordance with excisional biopsy results, 72,73 and they do not provide the histopathologic assessment of nodal architecture necessary for N staging. For personal use only.…”

Value of CT-guided core-needle biopsy in diagnosis and classification of malignant lymphomas using automated biopsy gun

“…The advantage of CT guidance is that the whole mediastinum or abdomen is visualized, allowing accurate planning of biopsy for deep and small lesions and avoiding damage to important organs and greater vessels [9,10] . In recent years, with the advance in new needle biopsy systems and technology of needle biopsy [11,12] , CT-guided core-needle biopsy is widely used in the diagnosis and classification of malignant lymphoma [13,14] . Since 1999, CT-guided core-needle biopsy has been used as one of the routine sampling techniques for malignant lymphomas in our hospital.…”

Fever of Unknown Origin Associated with Intrabdominal Lymphadenopathy, the Efficiency of Laparoscopic Biopsy

“…Unfortunately in our institution (and the wider health district) a PET-CT scan could not be performed. Computed tomography guided biopsies have been associated with a low morbidity and an acceptable diagnostic yield [6,7,18]. For these reasons percutaneous techniques are the gold standard in the diagnostic set up of abdominal lymphadenopathy.…”

“…Currently, ultrasound or computed tomography (CT)-guided biopsies are the gold standard for tissue sampling since they are minimally invasive procedures that are associated with low morbidity and acceptable diagnostic yield [4][5][6]. Nevertheless, in some cases tissue extraction via core-needle biopsy is not sufficient or tissue architecture is jeopardized and diagnosis cannot be established [6,7]. Furthermore, the proximity of an enlarged pathologic lymph node to vital structures such as major blood vessels, bowel or other viscera makes percutaneous biopsy technically difficult and dangerous even in the hands of an experienced radiologist [8].…”