Abstract:Background: Invasive Fungal Sinusitis(IFS) is seen in both immunocompromised and immunocompetent patients. All fungi elaborate uptake mechanisms to sequester iron, and produce siderophores with higher affinity for iron. The availability of iron and ability to utilize them are essential for viability and growth of Mucor and Aspergillus. Currently, IFS is dealt with surgical debridement and aggressive medical therapy. Amphotericin B being currently used in medical management. Considering the importance of iron i… Show more
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