Role of carboxamido nitrogen in mononuclear manganese complex: Superoxide scavenging activity and nuclease activity

Spontaneous Reduction of Mononuclear High‐Spin Iron(III) Complexes to Mononuclear Low‐Spin Iron(II) Complexes in Aqueous Media and Nuclease Activity via Self‐Activation

“…The tridentate Schiff base ligands Pyimpy and Me‐Pyimpy were synthesized according to the procedure reported earlier 11. Synthesis of monomeric iron(II) and iron(III) complexes were carried out in air.…”

Synthesis, structural characterization and DNA interaction studies on a mononuclear copper complex: Nuclease activity via self-activation

“…In IR spectra of 1, splitting of peaks near 1090 cm − 1 indicated the presence of coordinated perchlorate ion. However, solution conductivity measurement gave rise to 1:1 electrolyte [8]. Hence we speculate the dissociation of perchlorate ion in solution.…”

“…Redox property of the metal centre was examined by electrochemical studies. DNA interaction with calf thymus DNA (CT DNA) and nuclease activity with pBR322 plasmid were investigated and results of our mechanistic studies will be scrutinized in this communication.Schiff-base ligand Pyimpy (Scheme 1) was synthesized by the condensation of pyridine 2-aldehyde and 2-(1-phenylhydrazinyl) pyridine [8]. Pyimpy was reacted with Cu(ClO 4 ) 2 ·6H 2 O in methanol and a green solution was obtained.…”

“…Schiff-base ligand Pyimpy (Scheme 1) was synthesized by the condensation of pyridine 2-aldehyde and 2-(1-phenylhydrazinyl) pyridine [8]. Pyimpy was reacted with Cu(ClO 4 ) 2 ·6H 2 O in methanol and a green solution was obtained.…”

DNA interaction, SOD, peroxidase and nuclease activity studies of iron complex having ligand with carboxamido nitrogen donors

“…Bleomycin in presence of iron showed nuclease activity [10,11] where carboxamido nitrogen was ligated to metal centre. We have recently communicated the role of carboxamido nitrogen in superoxide scavenging activity as well as nuclease activity for iron and manganese complexes [12][13][14]. Moreover, it has been documented in literature that native SOD as well as small molecule SOD mimics exhibit nuclease activity [15,16].…”