Role of capsule endoscopy Pillcam COLON 2 in patients with known or suspected Crohn’s disease who refused colonoscopy or underwent incomplete colonoscopic exam: a case series

Negreanu, Lucian; Smarandache, G; Mateescu, Bogdan

doi:10.1007/s10151-013-1054-3

Cited by 30 publications

(24 citation statements)

References 21 publications

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“…CD tends to involve the terminal ileum and colon, and approximately 60% of patients with established CD have proximal small bowel lesions. 21,22 Several reports [23][24][25][26][27] assessed the role of CCE-2 in pan-enteric examinations for CD. D'Haens et al 23 compared CCE-2 and colonoscopy to assess disease severity in 40 patients with active colonic CD.…”

Section: Cce For Crohn's Diseasementioning

confidence: 99%

Colon Capsule Endoscopy for Inflammatory Bowel Disease

Hosoe¹,

Hayashi²,

Ogata³

2020

Clin Endosc

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Colon capsule endoscopy was initially introduced in 2006. Since the results of a prospective study to evaluate first-generation colon capsule endoscopy efficacy for the detection of colonic neoplasia were unsatisfactory, second-generation colon capsule endoscopy was developed and reported in 2009. In this review article, we provide an overview of the current state of colon capsule endoscopy for evaluation of inflammatory bowel disease in a clinical setting and describe our clinical experience with this technology and its application. Among the various types of inflammatory bowel diseases, ulcerative colitis is the primary target for application of colon capsule endoscopy. Nevertheless, the initial results of studies using first-generation colon capsule endoscopy to evaluate inflammation were unclear. More recently, second-generation colon capsule endoscopy has provided higher accuracy for assessment of inflammation in patients with ulcerative colitis. Colon capsule endoscopy enables noninvasive observation (with reduced volume preparation) of mucosal inflammation severity in patients with ulcerative colitis. Clin Endosc 2020 Jan 9. [Epub ahead of print]

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Section: Cce For Crohn's Diseasementioning

confidence: 99%

Colon Capsule Endoscopy for Inflammatory Bowel Disease

Hosoe¹,

Hayashi²,

Ogata³

2020

Clin Endosc

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“…To date, five studies have evaluated the performance of CCE‐2 with ileo‐colonoscopy or small bowel CE in suspected or confirmed CD (Table ). There are also studies that evaluated the role of CCE in routine clinical practice without comparing with a reference standard, in postoperative CD, and in CD patients who refused or had incomplete colonoscopy . The first multicenter European study has reported that CCE‐2 has a comparable sensitivity of 86% but a low specificity of 40% for ileo‐colonic ulceration in active CD .…”

Section: Cce In CDmentioning

confidence: 99%

Colon capsule endoscopy for inflammatory bowel disease

Jiao

Leung

2018

J of Digest Diseases

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Colon capsule endoscopy (CCE) is designed for direct visualization of the colonic mucosa through passive propulsion. The role of CCE in the detection of colonic polyps has been extensively evaluated. As mucosal healing has emerged as a pivotal target for treatment of inflammatory bowel disease (IBD), there is increasing data to suggest that CCE can also be used in the monitoring of mucosal inflammation in patients with active IBD, particularly in ulcerative colitis (UC) and Crohn's disease (CD). Despite advantages such as its non-invasive nature, patient's comfort, safety, and access to anatomical regions not easily reached by conventional endoscopy, CE has limitations including the lack of ability to obtain biopsies or therapeutic capabilities and no control over movement. In this review, the role and diagnostic value of CCE on diagnosis and monitoring of UC and CD patients, its safety and limitations are discussed.

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“…However, whether CCE is superior to conventional colonoscopy for assessment of disease activity and extent in UC remains controversial [34]. Although literature on use of CCE in Crohn's disease (CD) is sparse due to the concern of capsule retention caused by strictures, more recent studies demonstrate the safety and feasibility of use of CE in this disease [38][39][40][41][42]. In a multicenter pilot study, CCE-2 detected colonic ulcerations with 86 % sensitivity and 40 % specificity, and no adverse events were observed.…”

Section: Cce In Ibdmentioning

confidence: 99%

Colon capsule endoscopy: toward the future

Muguruma

Tanaka

Teramae

et al. 2017

Clin J Gastroenterol

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Colon capsule endoscopy is a wireless and minimally invasive technique for visualization of the whole colon. With recent improvements of technical features in second-generation systems, a more important role for colon capsule endoscopy is rapidly emerging. Although several limitations and drawbacks are yet to be resolved, its usefulness as a tool for colorectal cancer screening and monitoring disease activity in inflammatory bowel diseases has become more apparent with increased use. Further investigations, including multicenter trials, are required to evaluate the substantial role of the colon capsule in managing colorectal diseases.

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Role of capsule endoscopy Pillcam COLON 2 in patients with known or suspected Crohn’s disease who refused colonoscopy or underwent incomplete colonoscopic exam: a case series

Abstract: In this patient population, PillCam(®) COLON 2 capsule endoscopy was safe. The capsule findings had an important impact on treatment decisions and patient management.

Cited by 30 publications

References 21 publications

Colon Capsule Endoscopy for Inflammatory Bowel Disease

Colon Capsule Endoscopy for Inflammatory Bowel Disease

Colon capsule endoscopy for inflammatory bowel disease

Colon capsule endoscopy: toward the future

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