Role of Bronchoscopy in Lung Cancer Research

Baughman, Robert P.; Pina, Elsira M.

doi:10.1016/s0272-5231(05)70134-9

Cited by 2 publications

(2 citation statements)

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“…Markers found useful in the diagnosis of lung Ca include carcinoembryonic antigen, squamous cell carcinoma antigen, neuronspecific enolase, and cytokeratin fragments. 96 Markers suggestive of poor prognosis include the Kras mutation, TGF-␣, cathepsin B and p53. 96 The BAL also allows the scientist to study the inflammatory and immunological response to lung Ca.…”

Section: Researchmentioning

confidence: 99%

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Role of Bronchoscopy in Lung Cancer

Rafanan¹,

Mehta²

2000

Seminars in Respiratory and Critical Care Medicine

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Advancements in technology and experience have pushed forth the bronchoscope's increasing role in the struggle against lung cancer. The bronchoscope is useful in the following situations: diagnosis, staging, treatment of endobronchial lesions for palliation or cure, early detection of lung cancer, and research. In this article, we provide a concise overview of several endoscopic modalities (i.e., transbronchial needle aspiration, laser photoresection, photodynamic therapy, electrocautery, cryotherapy, brachytherapy, stents, autofluorescence bronchoscopy, and gene therapy). Basic principles, technique, indications, outcome data, and associated complications of each modality are discussed.

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Section: Researchmentioning

confidence: 99%

“…96 Markers suggestive of poor prognosis include the Kras mutation, TGF-␣, cathepsin B and p53. 96 The BAL also allows the scientist to study the inflammatory and immunological response to lung Ca. By measuring the local inflammatory response, response to treatment with immunomodulation can be assessed.…”

Section: Researchmentioning

confidence: 99%