Role of affect and personality in gastric acid secretion and serum gastrin concentration

The role of psychosocial factors in peptic ulcer disease: Beyond Helicobacter pylori and NSAIDs

“…Impulsivity was identified as the personality trait with the highest correlation coefficient (r=.82), with changes of gastric acid output during the acute mental stress period. Similarly, Feldman et al [48] found that basal gastric acid secretion was positively correlated with MMPI scale scores for impulsivity and social isolation. Bresnick et al [49] reported that a dichotomous listening task increased gastric acid secretion and that this increase was greater in duodenal ulcer patients than in control subjects.…”

“…Although no bulcer personality Q was observed, ulcer patients tended to be more hypochondriacal, pessimistic, and dependent. These same investigators subsequently reported that, compared with healthy control subjects, duodenal ulcer patients demonstrated variability in basal gastric acid secretion that correlated positively with MMPI scale scores for impulsivity and social isolation [48].…”

Stress and peptic ulcer: life beyond helicobacter

“…Gastric acid output is correlated with psychological distress in patients with and without ulcers,25 and increased enormously during intense military training 26. Compared with healthy people, patients with duodenal ulcers are particularly likely to respond to laboratory stressors by secreting more acid 27.…”

Psychometric properties of three personality inventories translated to Sinhalese

“…Personality may influence one's vulnerability to disorders, health-seeking behaviours and treatment compliance. A growing body of research provides evidence for the role of personality in certain mental health disorders including bipolar disorders (1), schizophrenia, substance abuse disorders (2,3) and eating disorders (4) as well as non-psychiatric diseases such as coronary artery disease (5), inflammatory bowel disease (6) peptic ulcer disease (7) and sleep disorders (8).…”