Role and application of glycosaminoglycans in trichology and cosmetology

Abstract

Glycosaminoglycans are structurally complex, linear polysaccharides. They show a hydrophilic effect and have the ability to bind water. In cosmetic preparations, they are obtained biotechnologically and appear in the form of hyaluronic acid, sodium hyaluronate and potassium hyaluronate. The aim of the study was to present the possibility of using glycosamidoglycans in cosmetology, trichology and aesthetic dermatology. These compounds are considered safe for topical application, they keep the skin in proper condition, support cell renewal, and increase the skin’s resistance to harmful external factors. They also bring satisfactory results in terms of application in trichology. A number of studies show that they stimulate hair growth, reduce excessive flaking of the scalp, seborrhea and support the treatment of androgenetic alopecia.

Glycosaminoglycans – types, structure, functions, and the role in wound healing processes

“…On the other hand, HA is very abundant during embryonic development, and in inflamemation, during healing, and within cancerous tumors. The largest amounts of HA are located in the dermis, cartilage and synovial fluid, the vitreous body of the eye, umbilical cord, heart muscle, kidneys, muscles, lymphatic system, mucous membranes, and also in the brain [2,5,51,53,55,62,63]. The basic function of HA is to bind and retain water in intercellular space, which determines the tissue resistance to mechanical loading.…”