Roentgen Therapy for Hyperhidrosis

Borak, J.; Eller, Joseph Jordan; Eller, William D.

doi:10.1001/archderm.1949.01520310051006

Cited by 17 publications

(5 citation statements)

References 3 publications

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“…They noted that mild sequelae could occur over 1600-1800 rad. Borak, Eller & Eller, (1949) did not find any sequelae in 122 patients with hyperhidrosis who had had less than 1600 rad through 2-4 mm Al. Sulzberger, Baer & Borota, (1952) in a survey of 763 patients irradiated for benign dermatoses matched with controls, concluded that there is no evidence that fractionated doses of superficial irradiation to a total of 1000 rad or less for benign dermatoses caused any sequelae, and that when total doses more than 1000 rad were given it may be expected that 1-5% of patients would show relatively mild roentgen sequelae of only cosmetic importance.…”

Section: Resultsmentioning

confidence: 74%

A follow-up study of superficial radiotherapy for benign dermatoses: recommendations for the use of X-rays in dermatology

Rowell

1973

Br J Dermatol

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SUMMARY One hundred out of 136 patients who had received either 1600 rad or more to the face, 1500 rad or more to the hands, 1600 rad or more to the finger nails, or 1600 rad or more to the feet for benign dermatoses during the years 1930 to 1964 were examined. Four patients had developed basal cell carcinomata of the face and one had developed a squamous cell carcinoma of the hands. Atrophy of the face and keratoses and telangiectasia of the hands occurred more frequently than in controls. It is concluded that superficial radiotherapy is a safe procedure for the treatment of benign dermatoses provided that no more than 1200 rad is given in fractionated doses to any area of skin over a lifetime. Recommendations are put forward to ensure that damage does not result from radiation.

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Section: Resultsmentioning

confidence: 74%

A follow-up study of superficial radiotherapy for benign dermatoses: recommendations for the use of X-rays in dermatology

Rowell

1973

Br J Dermatol

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“…5,14,[16][17][18][19][20][21][22] A familial trait for HH has been described, 23,24 and it has been estimated that 40% of patients have a family history of excessive sweating. 5 Ethnic predispositions have also been implicated; 8,21 however, contrary to the series of Adar et al 8 in which HH was observed among Jews originating from North Africa, Yemen, and the Balkans, being dark people, the majority of the subjects reported by Borak et al 7 were of light complexion. Cloward 24 found that in Hawaii, patients of Japanese origin were 20 times more likely to be affected than Caucasians.…”

Section: Introductionmentioning

confidence: 89%

“…The onset is usually either in early childhood, the youngest reported age being 3 months, 13 or adolescence-puberty, 8,14 and it seems to persist throughout life, 15 although it has been claimed that from the fourth decade of life the activity of the sweat glands has a tendency to decrease. 7 The vast majority of patients presenting for treatment are in the second or beginning of the third decade of life. [16][17][18][19][20][21][22] This is due to the early onset of symptoms and to the resulting occupational disabilities and social embarrassment which become especially prominent at this age.…”

Section: Introductionmentioning

confidence: 99%

“…3 It may develop secondary to a variety of medical disorders 4,5 or it may be primary, of unknown etiology. An exaggerated response, primarily to emotional stimuli, 6,7 but also to heat and physical effort, 7 has been implied. The major role of the emotional stimuli is emphasized by the observation that during sleep or under sedation, excessive sweating is not prominent, 3 while reports on HH from countries with predominantly cold weather indicate that a warm climate is not an important etiological factor.…”

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confidence: 99%

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The treatment of primary palmar hyperhidrosis: A review

2000

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Primary palmar hyperhidrosis (HH) is a pathological condition of overperspiration caused by excessive secretion of the eccrine sweat glands, the etiology of which is unknown. This disorder affects a small but significant proportion of the young population all over the world. Neither systemic nor topical drugs have been found to satisfactorily alleviate the symptoms. Although the topical injection of botulinum has recently been reported to reduce the amount of local perspiration, long-term results are required before a definitive evaluation of this method can be made. Hypnosis, psychotherapy, and biofeedback have been beneficial in a limited-number of cases. While radiation achieves atrophy of the sweat glands, its detrimental effects prohibit its use. Iontophoresis has attained some satisfactory results but it has not been assessed long term. Percutaneous computed tomography-guided phenol sympathicolysis achieves excellent immediate results, but its long-term failure rate is prohibitive. Furthermore, percutaneous radiofrequency sympathicolysis may be an effective procedure, but its long-term results are not superior to surgical sympathectomy. On the other hand, surgical upper dorsal (T2-T3) sympathectomy achieves excellent long-term results and the thoracoscopic approach has supplanted the open procedures. Despite some sequelae, mainly in the form of neuralgia and compensatory sweating which cannot be predicted and may be distressing, surgical sympathectomy remains the best treatment for palmar hyperhidrosis.

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“…Conservative treatment of hyperhidrosis with talcum, antiperspirant preparations containing aluminum salts, anti-cholinergics (atropine, Hydergine | Banthine| and tranquilizers may achieve temporary symptomatic relief at best. Destruction of the sweat glands by local application of formaldehyde or glutaraldehyde is usually inefficient, whereas good results have been reported for irradiation [4], although the effective dose of radiation may cause chronic dermatitis or even skin necrosis [5,6].…”

Section: Discussionmentioning

confidence: 99%

Transaxillary thoracic sympathectomy for primary hyperhidrosis of the upper limbs

et al. 1982

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Although a benign condition, primary hyperhidrosis of the upper limbs (palmar and axillary) may cause considerable psychological, social, and occupational disturbances. Definitive surgical treatment (i.e., upper dorsal sympathectomy) is justified after failure of conservative measures. Of the various surgical approaches to the upper thoracic sympathetic chain, one must select the approach that combines excellent results (cosmetic outcome included) with only minor and infrequent complications and side effects. Our experience with 70 thoracic sympathectomies (initially performed through a wide thoracotomy, currently by the transaxillary approach) followed up for an average of 25 months (range 1–87 months), corresponds with these strict criteria: 94% completely dry hands; 86% total, and an additional 10% partial, subjective satisfaction with the results; minimal and relatively mild side effects and complications. These results compare favorably with reports in the literature regarding thoracic sympathectomies performed through alternative approaches, indicating that the transaxillary approach is at least as good as the other approaches. At the same time, side effects and complications are less frequent and of a milder character with the transaxillary approach. We, therefore, recommend the axillary approach for thoracic sympathectomy in cases of hyperhidrosis of the upper limbs.

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Roentgen Therapy for Hyperhidrosis

Cited by 17 publications

References 3 publications

A follow-up study of superficial radiotherapy for benign dermatoses: recommendations for the use of X-rays in dermatology

A follow-up study of superficial radiotherapy for benign dermatoses: recommendations for the use of X-rays in dermatology

The treatment of primary palmar hyperhidrosis: A review

Transaxillary thoracic sympathectomy for primary hyperhidrosis of the upper limbs

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