The treatment of primary palmar hyperhidrosis: A review

Abstract

Primary palmar hyperhidrosis (HH) is a pathological condition of overperspiration caused by excessive secretion of the eccrine sweat glands, the etiology of which is unknown. This disorder affects a small but significant proportion of the young population all over the world. Neither systemic nor topical drugs have been found to satisfactorily alleviate the symptoms. Although the topical injection of botulinum has recently been reported to reduce the amount of local perspiration, long-term results are required before a definitive evaluation of this method can be made. Hypnosis, psychotherapy, and biofeedback have been beneficial in a limited-number of cases. While radiation achieves atrophy of the sweat glands, its detrimental effects prohibit its use. Iontophoresis has attained some satisfactory results but it has not been assessed long term. Percutaneous computed tomography-guided phenol sympathicolysis achieves excellent immediate results, but its long-term failure rate is prohibitive. Furthermore, percutaneous radiofrequency sympathicolysis may be an effective procedure, but its long-term results are not superior to surgical sympathectomy. On the other hand, surgical upper dorsal (T2-T3) sympathectomy achieves excellent long-term results and the thoracoscopic approach has supplanted the open procedures. Despite some sequelae, mainly in the form of neuralgia and compensatory sweating which cannot be predicted and may be distressing, surgical sympathectomy remains the best treatment for palmar hyperhidrosis.

Prevalence of heat and perspiration discomfort inside prostheses: Literature review

“…Moreover, it requires periodic injections to maintain effectiveness [11]. In some cases, hypnosis, psychotherapy, and biofeedback could be implemented to decrease sweating [77]. These methods have limited generalizability and usually are long-term solutions [77][78].…”

“…In some cases, hypnosis, psychotherapy, and biofeedback could be implemented to decrease sweating [77]. These methods have limited generalizability and usually are long-term solutions [77][78]. Many commercially available cooling systems are designed to decrease body temperature in athletes, soldiers, firefighters, and other professionals who need supportive clothes during long activities [79].…”

Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

“…Primer Hiperhidroz Primer hiperhidroz; nedeni iyi bilinmeyen, en sık palmoplantar ve/veya aksiller bölgede görülen, genellikle bilateral ve simetrik olarak ortaya çıkan aşırı terleme ile karakterizedir (2,(7)(8)(9). Palmoplantar hiperhidroz sıklıkla çocukluk veya adolesan çağda başlarken, aksiller hiperhidroz tipik olarak puberte ve sonrasında görülür (6)(7)(8).…”

“…Palmoplantar hiperhidroz sıklıkla çocukluk veya adolesan çağda başlarken, aksiller hiperhidroz tipik olarak puberte ve sonrasında görülür (6)(7)(8). Palmoplantar bölgedeki terleme serebral korteks tarafından kontrol edilir (10).…”

“…Ancak, terlemeyi azaltmak için gerekli olan dozlarda kullanıldıkları zaman bulanık görme, ortostatik hipotansiyon, üriner retansiyon ve taşikardi gibi yan etkilere yol açmaları en önemli dezavantajlarıdır (3,7). Ganglion bloke edici ajanlar geçmişte hiperhidroz tedavisinde başarılı bulunmuşsa da ortostatik hipotansiyon gibi ciddi yan etkilerin ortaya çıkması nedeniyle günümüzde tercih edilmemektedir (2).…”