Rodents

Hart, J. S.

doi:10.1016/b978-0-12-747602-5.50007-1

Cited by 49 publications

(20 citation statements)

References 447 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Physiologists have found major differences between the thermal physiology of mice, other mammals, and humans [3,[5][6][7][8][9][10][11][12], such that at ambient temperatures in which humans feel comfortable, mice experience chronic mild cold stress directly impacting their metabolism and thermoregulatory status. Laboratory mice are almost always housed and studied at mildly cool temperatures well below their 'thermoneutral zone' which is the ambient temperature in which metabolic heat production is minimal and the mouse does not need to work to keep warm or cold.…”

Section: Room Temperature: So Much More Than a Thermometer Readingmentioning

confidence: 99%

Thermoneutrality, Mice, and Cancer: A Heated Opinion

Hylander

Repasky

2016

Trends in Cancer

View full text Add to dashboard Cite

Section: Room Temperature: So Much More Than a Thermometer Readingmentioning

confidence: 99%

Thermoneutrality, Mice, and Cancer: A Heated Opinion

Hylander

Repasky

2016

Trends in Cancer

View full text Add to dashboard Cite

“…In small mammals running at temperatures below the thermal neutral zone, locomotor costs are often partially or fully additive to thermoregulatory expenditures, not substitutive, as is frequently the case in large mammals and birds (e.g. Wunder, 1970;Hart, 1971;Brooks and Fahey, 1984;Chappell et al, 2004;Webster and Weathers, 1990). As the weasels in our wheel respirometers were probably running at temperatures somewhat below their thermal neutral zone, the metabolic expenditures in excess of predicted values might be due to regulatory thermogenesis, not to transport costs per se.…”

Section: The Journal Of Experimental Biology 216 (4)mentioning

confidence: 99%

“…However, in several small mammals, substitution is minimal or incomplete [e.g. thermogenic costs must be added to transport costs (Wunder, 1970;Hart, 1971;Wunder and Morrison, 1974;Chappell et al, 2004)], and it is reasonable to assume this is also the case for weasels. The high summed costs of activity and temperature regulation are probably important drivers for the quite low activity of weasels in winter, which is part of an apparent seasonal trade-off between activity and thermoregulation that results in surprisingly constant DEE throughout the year (Zub et al, 2009).…”

Section: Energy Expenditures For Locomotion By Free-living Weaselsmentioning

confidence: 99%

The energy cost of voluntary running in weasels,Mustela nivalis

Chappell

Szafrańska

Zub

et al. 2012

Journal of Experimental Biology

View full text Add to dashboard Cite

SUMMARYThe small size and elongate shape of weasels (Mustela nivalis) probably evolved to facilitate movement within the burrow systems of prey species, but result in high energy costs of thermoregulation. In this study we measured metabolic rates of weasels during voluntary locomotion to determine whether energy costs of transport are also high in these unusually shaped mammals. In addition, we measured the lower and upper limits of aerobic metabolism [resting metabolic rate (RMR) and maximal oxygen consumption in forced exercise (V O2,max )], and used the wide size range of adult weasels to investigate the intraspecific scaling of energy metabolism. Finally, we combined measurements of energy use during running with radiotracking and doubly labeled water data from free-living weasels to estimate the importance of locomotor costs in daily energy budgets. We found that weasels have higher than predicted costs of running, largely because of an elevated intercept of the speed versus metabolic rate relationship. Running costs were strongly affected by the approximately fourfold range of body size in adults. As reported in other studies, the RMR of weasels was considerably higher than predicted from body mass. Maximal oxygen consumption was also higher than predicted, but factorial aerobic scope (V O2,max /RMR) was within the normal range for mammals. Intraspecific mass scaling of RMR and V O2,max did not differ from typical interspecific mammalian allometries. In wild weasels, locomotor costs comprised roughly 5% of daily energy expenditures; this low value was primarily a result of short travel times and distances.

show abstract

“…Since pelage insulation in the rat is not improved by artificial cold acclimation (Heroux, Depocas & Hart, 1959), an increased flow of heat to the environment can be assumed, and this is consistent with the observation that cold-acclimated rats maintain higher metabolic rates than non-acclimated controls (Depocas, Hart & H6roux, 1957;Heroux et al 1959). Cold appears to be the adequate stimulus for these adaptative changes (Hart, 1971) but its site and mode of action are not yet known. The effect of cold could be on the thermal sensors, and the induction of cold-acclimation be due to the prolonged activation of the neural structures or the effectors concerned with cold defence; on the other hand, the induction of cold-acclimation could be due, at least partly, to a direct effect of cold on peripheral tissues.…”

Section: Introductionmentioning

confidence: 99%

Autonomic thermoregulation after intermittent cooling of the spinal cord and cold exposure in the rat.

Banet¹,

Hensel²,

Pothmann³

1978

The Journal of Physiology

View full text Add to dashboard Cite

SUMMARY1 02 consumption, rectal and several skin temperatures were studied, at various ambient temperatures, in unanaesthetized rats that had been thermally stressed for an average of 290 h either by prolonged and intermittent cooling of the spinal cord or by prolonged and intermittent exposure to an ambient temperature which induced the same increase in 02 consumption as did the thermal stimulation of the spinal cord.2. At all the test ambient temperatures, both groups of thermally stressed animals maintained a metabolic level higher than that of the controls. In the animals previously exposed to cold the extent by which the metabolic rate was greater than that of the control animals was independent of ambient temperature; in those previously subjected to cooling of the spinal cord, however, it increased as the ambient temperature was lowered. Rectal and average skin temperatures were essentially unaffected by the treatments.3. It is concluded that prolonged and intermittent cooling of the spinal cord increases the gain of the temperature control system, whereas prolonged and intermittent cold exposure has no effect on it, and that these forms of thermal stimulation are therefore not equivalent.

show abstract

Rodents

Cited by 49 publications

References 447 publications

Thermoneutrality, Mice, and Cancer: A Heated Opinion

Thermoneutrality, Mice, and Cancer: A Heated Opinion

The energy cost of voluntary running in weasels,Mustela nivalis

Autonomic thermoregulation after intermittent cooling of the spinal cord and cold exposure in the rat.

Contact Info

Product

Resources

About