Robust quantitative SERS analysis with Relative Raman scattering intensities

Zhao, Fengtong; Wang, Weipeng; Zhong, Haodong; Yang, Fei; Fu, Wangyang; Ling, Yi; Zhang, Zhengjun

doi:10.1016/j.talanta.2020.121465

Cited by 24 publications

(16 citation statements)

References 29 publications

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“…The applications of SERS include sensing and imaging applications such as spectroelectrochemistry, single molecule SERS, and analytical and biological applications [45][46][47][48]. The power of SERS is its great ability to identify chemical species and to obtain accurate structural information regarding polymer and materials science, biochemistry and biosensing, catalysis, and electrochemistry [49,50]. Interestingly, SERS can also be used to investigate the orientation of single molecules, as reported by Moskovits et al [51].…”

Section: Theoretical Background Of Surface Enhanced Raman Spectroscopy Techniquesmentioning

confidence: 97%

A Comprehensive Review on Raman Spectroscopy Applications

et al. 2021

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Raman spectroscopy is a very powerful tool for material analysis, allowing for exploring the properties of a wide range of different materials. Since its discovery, Raman spectroscopy has been used to investigate several features of materials such carbonaceous and inorganic properties, providing useful information on their phases, functions, and defects. Furthermore, techniques such as surface and tip enhanced Raman spectroscopy have extended the field of application of Raman analysis to biological and analytical fields. Additionally, the robustness and versatility of Raman instrumentations represent a promising solution for performing on-field analysis for a wide range of materials. Recognizing the many hot applications of Raman spectroscopy, we herein overview the main and more recent applications for the investigation of a wide range of materials, such as carbonaceous and biological materials. We also provide a brief but exhaustive theoretical background of Raman spectroscopy, also providing deep insight into the analytical achievements.

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Section: Theoretical Background Of Surface Enhanced Raman Spectroscopy Techniquesmentioning

confidence: 97%

A Comprehensive Review on Raman Spectroscopy Applications

et al. 2021

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“…要利用 SERS 技术实现高效的 SARS-CoV-2 实时检测, 一个关键因素是活性基底的设计. 首先, SERS 活性基底材料除了常见的贵金属金 [46][47] 、银 [48] , 还发展出了石墨烯 [49][50] 、金属氧化物 [51][52][53] 等非贵金属材料, 金基底的生物相容性好、比较稳定, 但拉曼增强能力不如银基底; 银基底的拉曼增强效果最好, 但易发生氧化而不稳定; 石墨烯、金属氧化物等材料的拉曼增强效果一般, 但与检测物的亲合能力强. 因此, 结合不同材料的特点, 复合材料的 SERS 活性基底可进一步提升生物标志物检测器件的性能 [54][55][56] .…”

Section: Sers 技术unclassified

Research Progress on Nano Photonics Technology-based SARS-CoV-2 Detection^※

Yang¹,

Zhang²,

Su³

et al. 2022

Acta Chimica Sinica

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The worldwide outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the infection even death of people all over the world, which has gravely affected our daily life. Globalization of trade and convenient transportation immensely accelerate the propagation of the epidemic, which brings severe difficulties to prevent the epidemic. Therefore, rapid and accurate diagnosis of infected persons and screening of asymptomatic persons play an important role. At present, the most widely used method for the detection of SARS-CoV-2 is reverse transcription-polymerase chain reaction (RT-PCR), which still has some problems including complicated sample storage and transportation, complex operations and so on. These shortcomings cause the hindrances to achieve fast, simple, efficient diagnostic testing under the normalization of the epidemic. In the past few years, with the development of nanotechnology, bio-sensing methods based on nano photonics have become a research hotspot. Label-free optical methods have been widely explored for bio-sensing including virus detection, such as surface plasmon resonance (SPR), surface enhanced Raman scattering (SERS), whispering gallery mode (WGM) and colorimetry. These approaches offer available alternatives to improve the speed, sensitivity, and accuracy of optical bio-sensing, owing to the enhanced interaction between the nanostructure and the biomarkers. This review summarizes these nano photonics-based bio-sensing technologies for the detection of SARS-CoV-2. Moreover, the detection mechanism of biomarkers by nano photonics is explained, and the further development trends are discussed. In view of the difficulties in manufacturing nano photonics structures, a new strategy of large-area preparation of nano photonics structures using nano green printing technology is proposed, which provides theoretical and technical support for accurate and effective

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“…Using a Raman internal standard to correct fluctuation of the SERS signal is an effective method toward reliable quantitative SERS analysis. 101 3D SERS substrates have been recently designed by decorating noble-metal nanoparticles onto a 3D frame, which are dedicated to improve the uniformity of NPs. 94,102 Second, it is crucial to avoid the background interferences from the food matrix to improve the accuracy of the aptasensors.…”

Section: Challenges and Perspectivesmentioning

confidence: 99%

Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

Yan

et al. 2021

J. Agric. Food Chem.

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Owing to the excellent performances of high sensitivity, high specificity, on-site detection, and multiplexing capability, surface-enhanced Raman scattering (SERS)-based aptasensors have performed prosperous applications and gained impressive progress in food safety. Herein, we reviewed the SERS-based aptasensors from the principles to specific applications in food safety. First, the sensor-working principles, SERS label design and preparation are introduced. Then, the popular platforms in the aptasensors are summarized with their advantages and disadvantages, followed by their representative applications. Further, the specific applications of developing SERS-based aptasensors in food safety are systematically provided. Moreover, the multiplex analysis using SERS labels are highlighted. Finally, challenges and perspectives for improving the SERS-based aptasensor performance are also discussed, aiming to give some proposes for researchers to choose suitable SERS-based aptasensors according to specific applications.

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Robust quantitative SERS analysis with Relative Raman scattering intensities

Cited by 24 publications

References 29 publications

A Comprehensive Review on Raman Spectroscopy Applications

A Comprehensive Review on Raman Spectroscopy Applications

Research Progress on Nano Photonics Technology-based SARS-CoV-2 Detection^※

Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

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Robust quantitative SERS analysis with Relative Raman scattering intensities

Cited by 24 publications

References 29 publications

A Comprehensive Review on Raman Spectroscopy Applications

A Comprehensive Review on Raman Spectroscopy Applications

Research Progress on Nano Photonics Technology-based SARS-CoV-2 Detection※

Advances in Surface-Enhanced Raman Scattering-Based Aptasensors for Food Safety Detection

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Product

Resources

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Research Progress on Nano Photonics Technology-based SARS-CoV-2 Detection^※