“…Levels of transcription of hepatic GST alpha, rho and mGST3 isoforms increased in common carp after exposed to MC-LR at 50 g kg −1 , while the transcription of mu, theta and mGST isoforms were relatively stable and all the GST isoforms except GST kappa and rho recovered to original lev- els compared with controls at 72 h in carp (Fu and Xie, 2006). The transcription of GST alpha and mu in rats exposed to MC-LR at 50 g kg −1 was elevated at 3 h and mGST1 decreased at 6 h, while pi had no change at 3 and 6 h post-injection (Bulera et al, 2001). In a micro-array analysis, when mice were exposed to MC-LR at 75% LD 50 , transcription of the GST pi was elevated at 8 h, and GST Mu (Mu2 and Mu5 isoform) increased during 8-24 h (less than twofold compared with controls) .…”