Risk of tuberculosis in dialysis patients: association of tuberculin and 2,4-dinitrochlorobenzene reactivity with risk of tuberculosis

Christopoulos, Antonios; Διαμαντόπουλος, Αθανάσιος; Dimopoulos, Panagiotis; Gumenos, D. S.; Barbalias, George A.

doi:10.1007/s11255-006-9051-3

Cited by 15 publications

(16 citation statements)

References 15 publications

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“…Biological factors, such as advanced age and low BMI, are factors of immunological imbalance that influenced CMI responses of HD patients [24]. However, female HD patients enrolled in this study demonstrated a higher prevalence and risk of TB, even after allowing for the effect of the abovementioned factors.…”

Section: Discussionmentioning

confidence: 68%

Male–female differences in the risk of tuberculosis in dialysis patients

Christopoulos

Διαμαντόπουλος²,

Dimopoulos³

et al. 2008

Int Urol Nephrol

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Section: Discussionmentioning

confidence: 68%

Male–female differences in the risk of tuberculosis in dialysis patients

Christopoulos

Διαμαντόπουλος²,

Dimopoulos³

et al. 2008

Int Urol Nephrol

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“…A common finding associated with uremia is impaired immunity, including disorders of Tlymphocyte growth and activation, lymphopenia and decreased antigen-specific humoral immunity mediated by Tlymphocytes (12). In addition, several factors specific for HD patients, such as malnutrition, anemia, vitamin D deficiency and hyperparathyroidism, may further contribute to impaired immunity (13)(14)(15)(16). Therefore, HD patients are considered to have high susceptibility to TB, and latent TB is 52.5 times more likely to be reactivated in patients with renal failure than in the general population (1,17).…”

Section: Discussionmentioning

confidence: 99%

Tuberculous Osteomyelitis in the Ulna of a Patient Undergoing Hemodialysis

et al. 2013

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A 76-year-old woman on hemodialysis (HD) presented with pain and swelling in the left wrist and forearm. The osteomyelitis occurred in the part of the ulna adjacent to the arteriovenous fistula. Mycobacterium tuberculosis was identified in pus obtained from the left forearm, leading to a diagnosis of tuberculous osteomyelitis. The patient was treated with anti-tuberculous drugs and her symptoms improved. In this study, we report a case of tuberculous osteomyelitis occurring in the ulna, which is not the usual site of predilection for tuberculosis infection. As HD patients exhibit a high frequency of extrapulmonary tuberculosis, tuberculous osteomyelitis should be considered in the differential diagnosis of infectious osteomyelitis. In addition, it may be useful to perform stab cultures at an early stage in order to diagnose tuberculous osteomyelitis.

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“…The association between the IGRA conversion/ reversion and the preexisting risk for LTBI was also analyzed by adjustment to the other risk factors such as age, sex, duration of hemodialysis, diabetes mellitus, and the previous BCG vaccination using multivariate logistic regression analysis. 19 Variables for which the p value was less than 0.200 in the univariate analysis were included in the final model of the multivariate analysis. The agreement among test results was assessed using k coefficients.…”

Section: Discussionmentioning

confidence: 99%