Risk of maxillary fungus ball in patients with endodontic treatment on maxillary teeth: a case-control study

Association between maxillary sinus fungus ball and sinus bone grafting with deproteinized bovine bone substitutes: a case-control study

“…[1][2][3] The odontogenic theory is mainly explained by three interdependent factors related to the use of endodontic sealers containing zinc oxide. [1][2][3][4][5][6] The first factor is the creation of an oroantral communication, which acts as a route for the maxillary sinus contamination with the Aspergillus species. The second factor is the impairment of the normal ventilation and drainage clearance system, which is caused by the physical excess of the sealers within the sinus.…”

“…The second factor is the impairment of the normal ventilation and drainage clearance system, which is caused by the physical excess of the sealers within the sinus. [1][2][3][4][5][6] And the third factor is Aspergillus overgrowth, which is chemically elicited by the zinc itself. The explanation of the underlying mechanism leading to the development of FB related to Bio-Oss, as found in our study, can be only speculative and extrapolated by analogy to what has been previously mentioned for zinc oxide.…”

“…[1][2][3] Aspergillus fumigatus is, by far, the most frequent causative agent found in Europe, and the root canal overfilling with the passage of zinc oxide endodontic sealers into the maxillary sinus is the most commonly recognized risk factor for the development of FB in up to 84% of patients. [1][2][3][4][5][6] Although this form of sinusitis typically affects healthy adults and has a striking female predominance, several pathologic conditions, such as diabetes, immunodeficiency diseases, and immunosuppressive and chronic corticosteroid and antibiotic treatments have been pointed out as potential predisposing factors favoring the colonization and subsequent overgrowth of the fungal hyphae. [1][2][3] Since its first report in 1980 by Boyne and James, grafting of the maxillary sinus floor has rapidly become the most common surgical procedure used to increase the subantral alveolar bone height of the posterior maxilla for subsequent dental implant placement.…”

10.5937/mckg48-4337 = Non-invasive chronic fungal inflammation of the maxillary sinus mucosa as a cause of long-term cough: Case report

“…Prema prvom, veliki broj gljivičnih spora dospeva vazduhom kroz prirodno ušće u šupljinu paranazalnog sinusa (11). Prema drugom objašnjenju, kolonizacija i infekcija sluzokože maksilarnog sinusa odvija se preko jatrogene oroantralne komunikacije posle ekstrakcije bolesnog zuba, periodontalne destrukcije ili, još verovatnije, endodontskog tretmana, tokom kojeg se zubni kanal prepuni materijalom od teških metala (11). Moguća je i kombinacija ova dva mehanizma.…”

“…Kada teški metali, a naročito cink-oksid iz zubnog punjenja, dođu do šupljine sinusa, oštećuju mukocilijarni transport, čime se otežava prirodno eliminisanje gljivičnih spora koje su vazduhom dospele do sluzokože. Dalje, cink je poznat po sposobnosti da aktivira metabolizam mikroorganizama iz roda Aspergillus, da pospeši klijanje spora i ubrza rast gljivica (11,12). Studije su pokazale da u čak 84% slučajeva postoji udruženost gljivične lopte u maksilarnom sinusu i prethodnih stomatoloških intervencija na karioznim zubima (13).…”