Risk of congenital malformations in live-born singletons conceived after intracytoplasmic sperm injection: a Nordic study from the CoNARTaS group

Henningsen, Anna-Karina Aaris; Opdahl, Signe; Wennerholm, Ulla‐Britt; Tiitinen, Aila; Rasmussen, Steen; Romundstad, Liv Bente; Bergh, Christina; Gissler, Mika; Forman, Julie Lyng; Pinborg, Anja

doi:10.1016/j.fertnstert.2023.07.003

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…For instance, a recent meta-analysis [ 21 ] shows that singleton ART pregnancies have a higher risk of malpresentation compared to those conceived naturally. In addition, a study examining a large cohort from the Nordic registry showed that the risk of major malformations in live-born singletons was slightly higher after fresh ICSI compared with fresh IVF [ 22 ]. Finally, singletons appear to have a slighter higher risk of placenta previa compared to twin pregnancies [ 23 ], with estimates in both cases higher than those of naturally conceived pregnancies.…”

Section: Concepts Of Artmentioning

confidence: 99%

Assisted Reproductive Technologies: A New Player in the Foetal Programming of Childhood and Adult Diseases?

Faa,

Manchia,

Fanos

2024

Pediatric Reports

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Assisted reproductive technology (ART) is an emerging field in medicine that incorporates complex procedures and has profound ethical, moral, social, religious, and economic implications not just for the individuals who have access to this method but also for society. In this narrative review, we summarise multiple aspects of ART procedures and the possible consequences on the mother and newborn. Moreover, we provide an overview of the possible long-term consequences of ART procedures on the health of newborns, although longitudinal evidence is particularly scant. Users should be informed that ART procedures are not risk-free to prepare them for the possible negative outcomes that may occur in the perinatal period or even in childhood and adulthood. Indeed, risk estimates point to increased liability for major nonchromosomal birth defects; cardiovascular, musculoskeletal, and urogenital (in male newborns) defects; and any other birth defects. Less certainty is present for the risk of neuropsychiatric sequelae in children conceived through ART. Thus, its application should be accompanied by adequate counselling and psychological support, possibly integrated into specific multidisciplinary clinical programmes.

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Section: Concepts Of Artmentioning

confidence: 99%

Assisted Reproductive Technologies: A New Player in the Foetal Programming of Childhood and Adult Diseases?

Faa,

Manchia,

Fanos

2024

Pediatric Reports

View full text Add to dashboard Cite

show abstract

“…Data in this randomised trial 9 comparing health outcomes based on fertilisation methods remain insufficient. A Nordic study 11 from the CoNARTaS group found the risk of major malformations in liveborn singletons to be slightly higher after fresh ICSI compared with fresh IVF. These findings should be considered when choosing the ART method for couples without male factor infertility.…”

mentioning

confidence: 99%

Is intracytoplasmic sperm injection an add-on to conventional in vitro fertilisation for infertility without severe male factors?

Li,

Yang

2024

gocm

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Should I opt for intracytoplasmic sperm injection or should I not: high-tech no matter what?

Aghajanova

2024

F&S Reports

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Risk of congenital malformations in live-born singletons conceived after intracytoplasmic sperm injection: a Nordic study from the CoNARTaS group

Cited by 5 publications

References 28 publications

Assisted Reproductive Technologies: A New Player in the Foetal Programming of Childhood and Adult Diseases?

Assisted Reproductive Technologies: A New Player in the Foetal Programming of Childhood and Adult Diseases?

Is intracytoplasmic sperm injection an add-on to conventional in vitro fertilisation for infertility without severe male factors?

Should I opt for intracytoplasmic sperm injection or should I not: high-tech no matter what?

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