Risk of cancer in patients with biopsy-proven giant cell arteritis

Hill, Catherine; Cole, Antonia; Rischmueller, Maureen; Dodd, Thomas J.; Coleman, Mark; Tucker, Graeme; Roberts‐Thomson, Peter

doi:10.1093/rheumatology/kep409

Cited by 23 publications

(22 citation statements)

References 3 publications

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“…In this study, there was a trend toward increased incident cancers in the first year following GCA diagnosis (p ¼ 0.09), but this may have been related to detection bias [Kermani et al 2009]. In addition, a study from Australia of 226 temporal artery biopsy-positive GCA patients also found no overall increased risk of cancer in GCA patients compared with the general population [Hill et al 2010]. Finally, a recent study from Sweden evaluated cancer risk in PMR and GCA.…”

Section: Giant Cell Arteritiscontrasting

confidence: 50%

“…While the data are somewhat conflicting, most studies have concluded that there does not appear to be an increased risk of incident cancer in GCA [Hill et al 2010;Kermani et al 2009;Myklebust et al 2002]. Furthermore, even in the largest study which did report an increased risk of cancer, the risk was marginal and it was unclear whether the increased risk involved patients with GCA [Ji et al 2010].…”

Section: Giant Cell Arteritismentioning

confidence: 99%

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Malignancy Risk in Vasculitis

Kermani¹,

Warrington

Amin

2010

Therapeutic Advances in Musculoskeletal

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The vasculitides encompass a rare subset of autoimmune diseases. Reports of the concurrent association of malignancies with some forms of vasculitis raise the possibility that patients with certain types of vasculitis may be at increased risk of cancer. Conversely, some forms of vasculitis may be a manifestation of malignancy. We review cancer risk in patients with large vessel vasculitis (giant cell arteritis and Takayasu arteritis), polyarteritis nodosa, and the circulating antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides. In addition we discuss vasculitis as a paraneoplastic phenomenon, highlighting polyarteritis nodosa in association with hairy cell leukemia and reviewing the most common vasculitic manifestation of cancer, cutaneous vasculitis.

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Section: Giant Cell Arteritiscontrasting

confidence: 50%

Section: Giant Cell Arteritismentioning

confidence: 99%

Malignancy Risk in Vasculitis

Kermani¹,

Warrington

Amin

2010

Therapeutic Advances in Musculoskeletal

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“…Malignancy and Cardiovascular disease in Giant cell arteritis. Although suggested by some (244,245), the majority of studies have been unable to find an increased risk of malignancy in GCA ( 246,247,248,249,250,251). However, as GCA affects persons 50 years and older, particular attention should be paid to the development of concurrent neoplastic disease which is not uncommon in these age groups.…”

Section: Differential Diagnoses Malignancy and Cardiovascular Diseasementioning

confidence: 99%