Risk for prostate cancer by occupation and industry: A 24-state death certificate study

Krstev, Srmena; Baris, Dalsu; Stewart, Patricia A.; Hayes, Richard B.; Blair, Aaron; Dosemeci, Mustafa

doi:10.1002/(sici)1097-0274(199811)34:5<413::aid-ajim1>3.0.co;2-r

Cited by 58 publications

(61 citation statements)

References 55 publications

(79 reference statements)

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“…There were 140 cases of prostate cancer among whites, yielding a mortality odds ratio (MOR) of 1.2, 95% CI : 1-1.4 (Krstev et al, 1998b). There were 13 cases of prostate cancer among African Americans yielding a MOR = 2.2; 95% CI : 1.2-3.9 (Krstev et al, 1998b). The authors noted a significantly increased MOR of prostate cancer.…”

Section: Resultsmentioning

confidence: 96%

“…The results show a statistically significant positive odds ratio (OR) between firefighting and prostate cancer (OR = 1.22; 95% CI: 1.12-1.33) (Bates, 2007). Krstev, Burgess, Crutchfield, Storment, Gerkin, and Winston (1998a,b) performed two case studies on prostate cancer: a smaller study based on 981 pathologically confirmed prostate cancer cases (Krstev et al, 1998a) and a larger study based on 60,878 American men who died of prostate cancer (Krstev et al, 1998b). The smaller case study by Krstev et al (1998a) which was a case study on 981 new pathologically confirmed prostate cancer cases included 479 blacks and 502 whites who were diagnosed between 1986 and 1989, and 1,315 population controls (594 blacks and 721 whites).…”

Section: Resultsmentioning

confidence: 99%

“…Risk of prostate cancer mortality were shown to increase with increasing years of employment in firefighting (chi2 trend, p=0.02). Krstev et al (1998b) notes the prevalence of the chemical PAH in firefighting. There were 140 cases of prostate cancer among whites, yielding a mortality odds ratio (MOR) of 1.2, 95% CI : 1-1.4 (Krstev et al, 1998b).…”

Section: Resultsmentioning

confidence: 99%

“…Krstev et al (1998b) notes the prevalence of the chemical PAH in firefighting. There were 140 cases of prostate cancer among whites, yielding a mortality odds ratio (MOR) of 1.2, 95% CI : 1-1.4 (Krstev et al, 1998b). There were 13 cases of prostate cancer among African Americans yielding a MOR = 2.2; 95% CI : 1.2-3.9 (Krstev et al, 1998b).…”

Section: Resultsmentioning

confidence: 99%

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The Risk of Prostate Cancer from Occupational Exposures in Male Firefighters

Wong¹,

Gomes²

2011

RISS-IJHS

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Le cancer de la prostate est le cancer le plus fréquemment diagnostiqué chez les hommes. Étant donné qu'il se développe lentement, on peut prévenir la mortalité si on détecte et traite la tumeur alors qu'elle n'en est encore qu'à ses premiers stades de développement. On a démontré que des facteurs environnementaux pouvaient augmenter le risque de cancer de la prostate. Quelques recherches ont été effectuées sur les niveaux de cancer de la prostate chez les pompiers, mais peu d'articles ont été publiés à ce sujet. Cette étude vise à trouver une corrélation entre le métier de pompier et le niveau de cancer de la prostate. L'article indique des agents cancérigènes potentiels liés au métier de pompier. Cette étude analyse cinq articles ayant utilisé différentes méthodes d'obtention des cas et des cohortes étudiés, ainsi que diverses méthodes de comparaison. Néanmoins, les articles étudiés ont conclu à une corrélation positive entre le niveau d'exposition des pompiers dans le cadre de leur métier et le niveau de cancer de la prostate. Les produits chimiques suspectés d'être des agents cancérigènes par ces études sont les hydrocarbures aromatiques polycycliques (HAP) et la fumée d'incendie. Cependant, les études ultérieures devront être plus rigoureuses dans le calcul des niveaux de cancer de la prostate, en tenant compte de facteurs liés au style de vie, et d'autres variables confondantes comme le tabac et la durée estimée de l'exposition. Mots-clés :Pompier, exposition professionnelle, néoplasme de la prostate Abstract:Prostate cancer is the most commonly diagnosed cancer among men. Since prostate cancer is a slow developing cancer, mortality can be prevented if the tumour is detected and treated in its early stages. There is proof that environmental exposures can increase the risk of prostate cancer. Many papers have performed data analyses on prostate cancer levels in firefighters. There has been some research on firefighter prostate cancer levels but few reviews on the topic. This paper focuses on finding whether there is a correlation between firefighting occupation and levels of prostate cancer. As well, this paper notes potential carcinogens within the firefighting occupation. Five papers were included in this review; these papers used different methods to obtain the cases and cohorts for the study. The papers also used different controls for comparison. Nevertheless, the papers found in the search supported a positive correlation between exposures in firefighting occupations and the level of prostate cancer. The two chemicals that were suspected carcinogens in these studies were Polyaromatic hydrocarbons (PAH) and fire smoke. However, future research can be more rigorous in calculations of prostate cancer levels by including lifestyle factors, other confounders such as smoking, and estimated length of exposure.

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Section: Resultsmentioning

confidence: 96%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The Risk of Prostate Cancer from Occupational Exposures in Male Firefighters

Wong¹,

Gomes²

2011

RISS-IJHS

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“…The relationship between prostatic cancer and exposure to PAHs from coal was further explored according to confidence of assessment, 226 IARC MONOGRAPHS VOLUME 92 Table 2.17 and are of moderate magnitude (range, 1.3-2.0) and mostly of borderline significance. Krstev et al (1998) conducted a population-based case-control study in the USA that included 981 incident cases of prostatic cancer (479 African-American and 502 white men) diagnosed between 1986-89 and 1315 controls (594 African-American and 721 white men category matched by age and race), aged 40-79 years, who resided in Atlanta, Detroit and 10 counties in New Jersey that were covered by population-based cancer registries. Lifetime occupational history was obtained from the subjects and job titles were coded according to standard occupational codes.…”

mentioning

confidence: 99%

Integrating Field Analyses with Laboratory Exposures to Assess Ecosystems Health

Hellou¹,

Beach²,

Leonard³

et al. 2012

Polycyclic Aromatic Compounds

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initiated a programme on the evaluation of the carcinogenic risk of chemicals to humans involving the production of critically evaluated monographs on individual chemicals. The programme was subsequently expanded to include evaluations of carcinogenic risks associated with exposures to complex mixtures, life-style factors and biological and physical agents, as well as those in specific occupations. The objective of the programme is to elaborate and publish in the form of monographs critical reviews of data on carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations; to evaluate these data in terms of human risk with the help of international working groups of experts in chemical carcinogenesis Publications of the World Health Organization enjoy copyright protection in accordance with the provisions of Protocol 2 of the Universal Copyright Convention. All rights reserved.The International Agency for Research on Cancer welcomes requests for permission to reproduce or translate its publications, in part or in full. Requests for permission to reproduce or translate IARC publications -whether for sale or for noncommercial distribution -should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; email: permissions@who.int).The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the World Health Organization concerning the legal status of any country, territory, city, or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.The IARC Monographs Working Group alone is responsible for the views expressed in this publication. IARC Library Cataloguing in Publication Data NOTE TO THE READERThe term 'carcinogenic risk' in the IARC Monographs series is taken to mean that an agent is capable of causing cancer under some circumstances. The Monographs evaluate cancer hazards, despite the historical presence of the word 'risks' in the title.Inclusion of an agent in the Monographs does not imply that it is a carcinogen, only that the published data have been examined. Equally, the fact that an agent has not yet been evaluated in a Monograph does not mean that it is not carcinogenic.The evaluations of carcinogenic risk are made by international working groups of independent scientists and are qualitative in nature. No recommendation is given for regulation or legislation.Anyone who is aware of published data that may alter the evaluation of the carcinogenic risk of an agent to humans is encouraged to make this information available to the Section of IARC Monographs, International Agency for...

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