Risk Factors of Intra-familial Hepatitis B Virus Transmission among Hepatitis B Patients in Kupang, Indonesia

Kambuno, Norma Tiku; Bessie, Meylani Fernanda; Tangkelangi, Marni; Djuma, Agustina Welhelmina

doi:10.29313/gmhc.v7i2.4149

Cited by 7 publications

(8 citation statements)

References 19 publications

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“…30,31 In this study, HBsAg positivity in household contacts was 14.7%, confirming previous studies' results of high HBsAg prevalence in household contacts in Kupang. 15 The percentage of positive HBsAg in healthcare workers in Kupang was significantly high at 16.9%. As one of the high-risk population groups for HBV transmission, there is still no mandatory hepatitis B immunization program for healthcare workers in Indonesia.…”

Section: Discussionmentioning

confidence: 92%

“…22,23 Household contact with hepatitis B patients was also considered a high-risk population as they frequently share household items like razors, plates, cutlery, glassware, face towels, and toothbrushes. 15,29 Previous studies in several Asian countries have shown that the potential of HBV transmission from hepatitis B patients to those living in the same household is high. Especially for parents, siblings, or other household residents who were in close contact, share household items, have poor personal hygiene habits, and have previous blood transfusion history.…”

Section: Discussionmentioning

confidence: 99%

“…14 A similar study in Alak subdistrict, Kupang, in 2019 showed five out of 33 (15.2%) household contacts of 12 hepatitis B index patients were found positive for HBsAg. 15 A recent study reported a high prevalence of HBsAg (13.2%), antibody to HBsAg (anti-HBs), and antibody to hepatitis B core antigen (anti-HBc), 13.2%, 39.8%, and 28.7%, respectively, in a population of 341 high school students from Kupang (age 13-22). 16 A similar study in six orphanages in Kupang reported 15 HBsAgpositive children out of 310 subjects.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of Hepatitis B in Healthy Population in Kupang City, East Nusa Tenggara, Indonesia

Irfan¹,

Kambuno

Budiana

et al. 2023

Glob Med Health Commun

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Hepatitis B virus (HBV) infection has remained a global health problem. Around 2 billion people worldwide are infected, and more than 257 million are categorized as chronic patients with a risk of developing progressive liver diseases, such as cirrhosis, liver failure, and hepatocellular carcinoma. In 2013, East Nusa Tenggara province had the most hepatitis B cases in Indonesia. Several factors cause a lack of information on HBV prevalence in the general population. First, they are inadequate disease surveillance systems with a high possibility of some acute and chronic infections being unreported. Second, geographical barriers to achieving suitable and sufficient data collection, considering the total population of 250 million people distributed in more than 17,000 islands. Third, the limited testing facilities for detecting chronic HBV resulted in many people being undiagnosed. This study was conducted to discover the prevalence of hepatitis B in healthy populations. It was a cross-sectional study with a random sampling method from April 2016 to March 2020 in Kupang city, East Nusa Tenggara. Subjects are prison inmates, pregnant women, primary school students, high school students, health workers, orphanage children, and families who live under the same roof with hepatitis B patients. We screened 11,152 subjects for HBsAg positivity using the ELISA and rapid detection tests. We found that 1,490 subjects (13.3%) were reactive to HBsAg. This HBsAg-positive prevalence stood far above the national rate of 7.1% in 2013, meaning that Kupang city is a region with high hepatitis B endemicity. Therefore, the local government should develop prevention strategies, diagnosis, post-infection management, and effective treatment, including mass vaccination programs for at-risk groups.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Hepatitis B in Healthy Population in Kupang City, East Nusa Tenggara, Indonesia

Irfan¹,

Kambuno

Budiana

et al. 2023

Glob Med Health Commun

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“…The risk for HBV infection in the seasonal migration group was 4.3 times higher compared to local workers (p=0.00; OR=4.3; 95% CI=2.2-8.4), with a prevalence rate of 11%. 18 The importance of the HBV screening test of pregnant women was also carried out by Yi et al 19 and Kambuno et al 20 Their study suggested screening pregnant women to find out whether they are infected with hepatitis B. Early immunization of babies born to women infected with hepatitis B is highly recommended, and check HbsAg for those women going to marry.…”

Section: Discussionmentioning

confidence: 99%

Determinants of Detectable Anti-hepatitis B in Fertile Age Women from Indonesia

Pracoyo

Suratri

Senewe

et al. 2022

Glob Med Health Commun

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Hepatitis B (HBV) is still a major health problem worldwide, as evidenced by the large number of people infected with hepatitis. There are around two billion people infected with HBV, and an estimated 350 million are in chronic conditions. Hepatitis B is a ninth-order disease that causes death in mothers and their babies. The HBV infection in pregnant women is critical because of vertical or perinatal transmission. This study's purpose was to analyze data of the HBsAg and anti-HBs rertile age women, pregnant women, and postpartum mothers from National Basic Health Research Data 2007. The method is a retrospective study using secondary data from the Basic Health Research in 2007. The number of samples in the form of data on respondents of fertile age women are women aged 15 to 49 years. Data screened and matched with that examined pregnancy/have had a postpartum examination/never checked neonates/had examined their toddlers. One thousand three hundred two (1,302) respondents were eligible to be sampled in this analysis. The variables analyzed were age and anti-HB titers in women of childbearing age 15 to 49 years who were not protected against hepatitis B, as much as 74.65% of the total 1,302 people. Three hundred thirty (330) respondents had anti-HBs titers. This study concludes respondents who are not married age 15–20 years showed relationship with negative anti-Hbs antibodies.

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“…Penularan horizontal VHB dapat terjadi melalui berbagai cara yaitu penularan perkutan, melalui selaput lendir atau mukosa (Pusparini & Ayu, 2017). Hepatitis B dapat menyerang dengan atau tanpa gejala Hepatitis (Kambuno, Bessie, Tangkelangi, & Djuma, 2019). Pada kehamilan, risiko terinfeksi virus HBV sebenarnya sama dengan wanita tidak hamil di usia yang sama dan dapat timbul di ketiga trimester kehamilan.…”

Section: Pendahuluanunclassified

Factors Related to Hepatitis B in Pregnant Women

Atmaja¹

2022

jaia

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The prevalence of hepatitis is 0.4% of the population in Indonesia, of which 1-5% are pregnant women with hepatitis B virus. The purpose of this study was to determine the relationship between maternal characteristics, knowledge of hepatitis B, prevention attitudes, family history, immunization history, sexual activity, traditional medicine and rest with the incidence of Hepatitis B in Cirebon Regency in 2020. Analytical study with a case-control approach with Chi-square test and logistic regression. The number of samples using the Stanley Lemeshow formula obtained 42 people, taken by purposive sampling at the Waruroyom and Mundu Health Centers. Family history of hepatitis was only found in pregnant women with hepatitis B, namely 2 people (21.4%) with a p value of 0.32 and an OR value of 3.545 with a confidence interval between 2.149 to 5.850. The majority of pregnant women with hepatitis B did rest 6 hours/day that is 10 people (71.4%) while those who do not have hepatitis B majority do rest <6 hours/day that is 20 people (71.4%) with p value 0.021 and OR value 0.160 with a confidence interval of 0.039 to with 0.662. Variables related to the incidence of Hepatitis B in pregnant women are education, traditional medicine and rest. The greatest and smallest relationship strengths were education (OR:154,324) and rest (OR:18,932). Pregnant women with low education need to be given information or health education about hepatitis.

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Risk Factors of Intra-familial Hepatitis B Virus Transmission among Hepatitis B Patients in Kupang, Indonesia

Cited by 7 publications

References 19 publications

Prevalence of Hepatitis B in Healthy Population in Kupang City, East Nusa Tenggara, Indonesia

Prevalence of Hepatitis B in Healthy Population in Kupang City, East Nusa Tenggara, Indonesia

Determinants of Detectable Anti-hepatitis B in Fertile Age Women from Indonesia

Factors Related to Hepatitis B in Pregnant Women

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