Risk Factors in Pulmonary Tuberculosis Treatment Failure

Nugrahaeni, Dyan Kunthi; Rosmalaningrum, Lala

doi:10.20473/ijph.v16i1.2021.12-22

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…In addition, men often move outside the home to earn a living, so they tend not to take OAT on time as recommended by health workers. [10][11][12][13]…”

Section: Resultsmentioning

confidence: 99%

Factors Related to Adherence to Taking Anti-Tuberculosis (OAT) Drugs in Pulmonary Tuberculosis Patients at Cut Meutia General Hospital, North Aceh Regency

Sahputri

Khairunnisa

2022

OAIJMR

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Tuberculosis (TB) is a disease with a high risk of transmission and is one of the diseases whose cases continue to increase and cause death worldwide. Until now, pulmonary tuberculosis has been difficult to treat because of the patient's non-compliance with taking anti-tuberculosis drugs (OAT). This study aims to investigate the factors associated with adherence to taking OAT drugs in tuberculosis patients at Cut Meutia General Hospital. This research is an observational study with a cross-sectional design. The study was conducted at the pulmonary disease polyclinic of Cut Meutia General Hospital, North Aceh Regency. The study was conducted on 100 patients, with the sampling technique being total sampling. The sample inclusion criteria in this study were patients who had been diagnosed with pulmonary tuberculosis, were willing to participate in the study, and had signed an agreement to participate in the study. A total of 100 patients participated in this study. Most of the patients were male (64%), aged over 46 years (52%), had low education (75%), had difficult hospital access (70%), and had poor knowledge regarding TB treatment (60%). In conclusion, the factors of age, gender, and distance of residence are related to adherence to taking OAT. Meanwhile, education and knowledge are not related to adherence to taking OAT in pulmonary TB patients at Cut Meutia General Hospital, North Aceh Regency.

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“…In addition, men often move outside the home to earn a living, so they tend not to take OAT on time as recommended by health workers. [10][11][12][13]…”

Section: Resultsmentioning

confidence: 99%

Factors Related to Adherence to Taking Anti-Tuberculosis (OAT) Drugs in Pulmonary Tuberculosis Patients at Cut Meutia General Hospital, North Aceh Regency

Sahputri

Khairunnisa

2022

OAIJMR

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“…Adherence is defined as the extent to which a person's behavior in taking medication, following changes in diet and/or lifestyle, is in accordance with agreed recommendations from healthcare practitioners (6). There are many factors related to TB treatment adherence such as personal characteristics, relationship between healthcare providers and patients, treatment regimens and healthcare settings (3). WHO states that there are five dimensions of medication adherence, namely social and economic factors, therapy-related factors, disease-related factors, patient-related factors, and healthcare system-related factors.…”

Section: Discussionmentioning

confidence: 99%

Factor Affecting Treatment Compliance in TB Patients

Lucya

Arief²

2022

Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal)

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Aims: Pulmonary Tuberculosis is a disease caused by Mycobacterium tuberculosis that invades the lungs. Indonesia ranks second as the country with the highest number of pulmonary TB in the world. The treatment coverage of Pulmonary TB in Indonesia in 2022 is only 25% of the target (80%). One of the risk factors that cause treatment failure is medication adherence. Objective: This study aims to determine the factors that influence medication adherence in patients with pulmonary TB. Methods: This study used a quantitative descriptive design with a cross-sectional study on 33 patients with pulmonary TB who became respondents by using total sampling. This study uses more than one instrument including Morisky Medication Adherence Scale-8, Generic Assessment of Side Effects, Multidimensional Scale of Perceived Social Support. The data analysis that were used in this study are Pearson Product Moment, Chi-square, Kruskal-wallis, and Simple Linear Regression. Results: The results of this study on factors related to medication adherence on TB patients showed that age, level of education, duration of treatment, drug side effects, and family support were related to medication adherence of pulmonary TB patients. alone. Conclusion: This study showed that to achieve medication adherence requires the continuity of various factors and does not depend on one factor Future researchers are expected to examine other factors that can affect medication adherence in patients with Pulmonary TB.

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“…13 Moreover, because males frequently leave the house in search of employment, they are less likely to take their OAT medication at the prescribed times, as advised by medical professionals. 13,21,22 According to the studies cited above, there are significant disagreements on the effectiveness of treatment dependent on a patient's gender. Due to the fact that this study has a number of limitations, such as a small sample size and a single-center study, as well as the fact that the ratio of female participants to total participants is quite low, so these findings cannot be definitively applied.…”

Section: Discussionmentioning

confidence: 99%

Frequency of Tuberculosis and its Outcomes After Anti-Tuberculosis Treatment According to Age and Gender

Maheshwari¹,

Qabulio²,

Kumar³

et al. 2022

PJMHS

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Objective: To determine the frequency of pulmonary tuberculosis and its outcomes after anti-tuberculosis treatment according to age and gender. Methods: This cross-sectional study was conducted at the department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre Karachi, with the collaboration of different DOTs centers and chest ward JPMC, Karachi Medical and Dental College, Karachi. All newly diagnosed pulmonary tuberculosis patients who registered for treatment, of either gender, were included. All the patients were followed until the end of the treatment, and they were assessed regarding treatment outcomes in terms of the success and failure of the treatment according to the age and gender of the patients. A self-made proforma was structured to collect the information, and SPSS version 26 was used for the purpose of data analysis. Results: A total of 237 cases were observed, their mean age was 41.80+16.44 years and their mean weight was 51.09+7.90 kg. Males were in majority 84.0% and females were 16.0%. The majority of cases (96.2%) had completed treatment, while 3.8% of cases had not yet completed treatment.91.0% of the patients were cured, while the remaining 8.40% were still not cured during the study period. Treatment outcome was statistically significant according to age (p = 0.001), while statistically insignificant according to gender (p = 895). Conclusion: As per the study conclusion, the frequency of pulmonary tuberculosis was frequently higher among males compared to females. Treatment outcome was influenced by age greater than 60 years, while no gender effects were observed. Keywords: Tuberculosis, age, gender, treatment

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Risk Factors in Pulmonary Tuberculosis Treatment Failure

Cited by 6 publications

References 13 publications

Factors Related to Adherence to Taking Anti-Tuberculosis (OAT) Drugs in Pulmonary Tuberculosis Patients at Cut Meutia General Hospital, North Aceh Regency

Factors Related to Adherence to Taking Anti-Tuberculosis (OAT) Drugs in Pulmonary Tuberculosis Patients at Cut Meutia General Hospital, North Aceh Regency

Factor Affecting Treatment Compliance in TB Patients

Frequency of Tuberculosis and its Outcomes After Anti-Tuberculosis Treatment According to Age and Gender

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