Factor Affecting Treatment Compliance in TB Patients

Abstract

Aims: Pulmonary Tuberculosis is a disease caused by Mycobacterium tuberculosis that invades the lungs. Indonesia ranks second as the country with the highest number of pulmonary TB in the world. The treatment coverage of Pulmonary TB in Indonesia in 2022 is only 25% of the target (80%). One of the risk factors that cause treatment failure is medication adherence. Objective: This study aims to determine the factors that influence medication adherence in patients with pulmonary TB. Methods: This study used a quantitative descriptive design with a cross-sectional study on 33 patients with pulmonary TB who became respondents by using total sampling. This study uses more than one instrument including Morisky Medication Adherence Scale-8, Generic Assessment of Side Effects, Multidimensional Scale of Perceived Social Support. The data analysis that were used in this study are Pearson Product Moment, Chi-square, Kruskal-wallis, and Simple Linear Regression. Results: The results of this study on factors related to medication adherence on TB patients showed that age, level of education, duration of treatment, drug side effects, and family support were related to medication adherence of pulmonary TB patients. alone. Conclusion: This study showed that to achieve medication adherence requires the continuity of various factors and does not depend on one factor Future researchers are expected to examine other factors that can affect medication adherence in patients with Pulmonary TB.

Factors Affecting Treatment Adherence Among Patients with Tuberculosis in Indonesia: Literature Review

“…Lucya & Arief's (2022) research also found that family living was significantly associated with medication adherence (p-value 0.018) (38). Family support in the form of financial assistance, affection, attention, enthusiasm, and motivation helps patients to comply with treatment (37).…”

“…Older people tend to follow doctors' instructions because they are more responsible, orderly, conscientious, moral, and filial compared to younger people. Older patients tend to be more adherent to treatment because their activity is less dense compared to younger patients so they can seek treatment regularly (38).…”

“…Based on research by Lucya & Arief (2022) shows that adherence to taking medication is significantly related to treatment ((p-value 0.027). The duration of TB treatment is quite long, which is about 6-9 months, causing TB patients to feel saturated and tired which results in decreased adherence to taking drugs.…”

“…The duration of TB treatment is quite long, which is about 6-9 months, causing TB patients to feel saturated and tired which results in decreased adherence to taking drugs. In addition, the symptoms experienced by patients began to decrease, especially at 2 months of treatment, and the side effects of drugs felt by patients caused patients to be lazy to seek treatment, even though at the beginning of treatment there was counseling about the treatment of Pulmonary Tuberculosis (38).…”

“…Patients who experience side effects decide to stop taking the given medication due to their ignorance about the side effects of the drug. As for patients who remain adherent to taking medication despite experiencing side effects influenced by other variables (38).…”