Risk Factors in Bacterial Meningitis: Charleston County, South Carolina

Fraser, David W.; Darby, Charles P.; Koehler, Robert E.; Jacobs, Cecil F.; Feldman, Roger A.

doi:10.1093/infdis/127.3.271

Cited by 119 publications

(18 citation statements)

References 14 publications

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“…Of the 34 patients in whom no organism was identified, six (17-7%) were known to have had antibiotic therapy before hospital admission. Spneumoniae was the most common causative organism, accounting for 49% of identified cases, and was associated with the highest case Seizures before or during hospita were recorded in 16 Drought history of head injury (two died), and 2 period patients had predisposing or concurrent illnesses (chronic otitis media and pneumonia). Fifteen cases of tuberculosis meningitis were reported, of whom nine were adults and two were infants.…”

Section: Resultsmentioning

confidence: 99%

Bacterial meningitis in Swaziland: an 18 month prospective study of its impact.

Ford

Wright

1994

Journal of Epidemiology & Community Health

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Section: Resultsmentioning

confidence: 99%

Bacterial meningitis in Swaziland: an 18 month prospective study of its impact.

Ford

Wright

1994

Journal of Epidemiology & Community Health

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“…Our findings of a low meningococcal colonisation rate in black patients might be explained if they acquired meningococcal infections at an earlier age with a resulting immunity as adults. However, the incidence of meningococcal meningitis is the same or slightly higher among white compared with black children, whereas the incidence of pneumococcal and haemophilus meningitis is higher in black children (Fraser et al, 1973;Floyd et al, 1974). Racial differences have been described in the pharyngeal colonisation of another pathogenic micro-organism.…”

Section: Discussionmentioning

confidence: 99%

Pharyngeal colonisation by Neisseria gonorrhoeae and Neisseria meningitidis in black and white patients attending a venereal disease clinic.

Noble¹,

Cooper²,

Miller³

1979

Sexually Transmitted Infections

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SUMMARY Pharyngeal colonisation by Neisseria gonorrhoeae and Neisseria meningitidis was studied in 2000 patients attending a venereal disease clinic. Of these patients, 64 % were white and 36% were black. The incidence of gonococcal infections was highest in the period from June to August. The incidence of genital or rectal infections or both was higher in the black patients. Pharyngeal colonisation by gonococci was present in 1 3 % of the patients. There were no significant associations between pharyngeal colonisation and the pharyngeal symptoms, race, sex, or marital state of the patients. Pharyngeal colonisation was more frequent in patients with gonococcal infections at other sites. However, in 40 7 % of the patients with pharyngeal colonisation, the pharynx was the only culture-positive site. There was no significant difference in the auxotypes or in the antibiotic susceptibility of the pharyngeal and the rectal-genital isolates except in the susceptibility to spectinomycin. Our findings do not indicate that gonococci isolated from the pharynx differ significantly from gonococci isolated from rectal or genital sites. It was notable that meningococcal colonisation of the pharynx was significantly more frequent in the white patients. This may be a genetically determined phenomenon.

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“…Hib causes an estimated 10 000 meningitis cases annually in the United States, primarily in children 2 mo to 5 y old (1)(2)(3)(4). The mortality rate due to Hib meningitis ranges from 5 to lo%, with about 40% of the survivors developing some degree of permanent neurologic impairment.…”

mentioning

confidence: 99%