Risk Factors for Urinary Tract Infection in Hospitalized Patients

Setyorini, Hadiati; Mardiana, Nunuk; Tjempakasari, Artaria

doi:10.20473/bhsj.v2i1.11549

Cited by 7 publications

(7 citation statements)

References 17 publications

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“…This result was supported by other previous studies in Indonesia and other countries as well (Ren et al 2016, Pratistha et al 2018, Setyorini et al 2019. Fimbriae, flagella, toxins, pili, curli, and iron acquisition systems are some virulence factors that help E. coli cause infection (Terlizzi et al 2017).…”

Section: Microbiological Investigationsupporting

confidence: 82%

“…Nearly 74% of the E. coli strain in this study was an ESBL-producing strain. Another study in the same area that used data in the year 2018 mentioned that only 34.78% of the E. coli strain produces ESBL in hospitalized patients (Setyorini et al 2019). The data indicated that there was a rapid spreading of the ESBL gene in the clinical environment as Indonesia is a country where there is the emersion and transmission of ESBL genes harbored inside the bacterial strains (Severin et al 2010).…”

Section: Microbiological Investigationmentioning

confidence: 99%

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Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia

Utami

Wahyunitisari

Mardiana

et al. 2022

FMI

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Highlights: Most urinary tract infections are caused by Gram-negative bacteria with E. coli being the most common bacteria. Antibiotics with the highest susceptibility for Gram-negative bacteria were ertapenem, meropenem, amikacin, and imipenem. Antibiotics with the highest susceptibility for Gram-positive bacteria mainly were susceptible to chloramphenicol,streptomycin, vancomycin, rifampin, tigecycline, teicoplanin, and ampicillin. Abstract: Urinary tract infection (UTI) is one of the most common bacterial infections. Inappropriate antibiotic use for UTI treatment may lead to antibiotic resistance. This study aimed to provide an updated bacterial and antibiogram profile from urine specimens of patients diagnosed with UTI. This study was a retrospective study using urine culture and antibiotic susceptibility test results obtained from Clinical Microbiology Laboratory in a tertiary general hospital in Surabaya, Indonesia for a two-month period patients. Most aged more than and/or equal to 59 years, in both sexes. Gram-negative bacteria, particularly , was being the most between June to July 2019. There were 215 patients with significant urine culture results of 54.4% from Escherichia coli female bacteria were carbapenem antibiotics and amikacin, while teicoplanin and vancomycin were some antibiotics susceptible to gramcommon bacteria that caused UTI, followed by K. pneumoniae. Some antibiotics with the highest susceptibility to gram-negative positive bacteria. This study result indicated that there was an urge to conduct local antibiogram profile investigation due to the low susceptibilities shown in recent empirical therapy recommendations, such as trimethoprim sulfamethoxazole, fluoroquinolone, nitrofurantoin, and fosfomycin.

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Section: Microbiological Investigationsupporting

confidence: 82%

Section: Microbiological Investigationmentioning

confidence: 99%

Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia

Utami

Wahyunitisari

Mardiana

et al. 2022

FMI

Self Cite

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“…This is consistent with an earlier study by Hariati et al (2019) who found that CAUTI was more prevalent in people over 60 years old. Older age and immobility were two additional significant risk variables, although they could be influenced by other factors (Setyorini et al 2019). Patients with diabetes mellitus have a significant risk of developing urinary tract infections since their urine is a source of microbial growth, and they typically have immunocompromised states.…”

Section: Patient Characteristicsmentioning

confidence: 99%

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Ahmad Veri Erianto,

Tri Pudy Asmarawati,

Agung Dwi Wahyu Widodo

et al. 2023

FMI

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Highlights: This study examined patients with catheter-associated urinary tract infections (CAUTI) to find the prevalent bacteria and the frequency of antibiotic use. Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli sensitive to amikacin was found to be the most common pathogen in CAUTI, while ceftriaxone was the most commonly used antibiotic. Abstract Catheter-associated urinary tract infection (CAUTI) is the most typical type of infection associated with healthcare. This infection constitutes a significant health problem due to its complications and frequent recurrence. The high annual incidence of CAUTI leads to infectious complications and a high cost of treatment. Antibiotic-resistant bacteria further complicate the problem because multiresistant pathogenic bacteria are often responsible for these infections. Moreover, the lack of a comprehensive case reporting system in Indonesia hinders the determination of CAUTI incidence. This study aimed to determine the bacterial profile and antibiotic use in CAUTI patients (n=22) at the Internal Medicine Inpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. This retrospective descriptive study collected data from patient medical records to describe the incidence, type of bacteria, sensitivity patterns, and antibiotic use in CAUTI patients. The data collection process included collecting medical records, recording information on data collection sheets, and recapitulating and analyzing the data. The criteria for CAUTI diagnosis were a bacterial count of ≥105 CFU/mL and a catheterization that lasted more than 48 hours. Samples were selected using non-probability sampling, also known as saturation sampling. Meanwhile, variables analyzed in this study were the type of pathogenic bacteria, antibiotics used, age, and sex. Descriptive analysis was employed to analyze the data. The findings suggested that the most common bacteria were Escherichia coli, with eight of nine bacteria showing extended-spectrum beta-lactamase (ESBL) production. Female patients aged 35–65 years were the majority of the CAUTI patients. Amikacin was the antibiotic with the highest sensitivity (90.9%), while ceftriaxone was the most common type of antibiotic administered to the patients. In addition, intravenous (IV) administration was the most common route of antibiotic administration, with an average therapy duration of seven days. In conclusion, identifying the type of pathogenic bacteria and performing antibiotic susceptibility testing can help minimize antibiotic resistance and prevent more severe complications in CAUTI patients.

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“…Santosaningsih et al (2018) dalam penelitiannya menemukan bahwa 257 dari 567 (45,3%) pasien rawat jalan pada 10 fasilitas kesehatan di Pulau Jawa dan Bali mengalami infeksi kulit dan jaringan lunak karena Staphylococcus aureus. Sedangkan, pada penelitian yang dilakukan oleh Setyorini et al (2019) menyatakan bahwa Escherichia coli menjadi patogen yang paling banyak menyebabkan infeksi saluran kemih dibandingkan 25 spesies bakteri lain yang diuji pada pasien rawat inap di RSUD dr. Soetomo, Surabaya, yaitu sebanyak 41,3%, oleh karena itu, Escherichia coli dan Staphylococcus aureus menjadi bakteri yang sering menyebabkan infeksi terkait pelayanan kesehatan sehingga dibutuhkan media pertumbuhan bakteri yang memadai pada laboratorium di pelayanan kesehatan untuk menegakkan diagnosis infeksi akibat kedua bakteri tersebut. Berdasarkan uraian fenomena di atas, maka perlu untuk melakukan penelitian dengan menjadikan limbah ikan bandeng (Chanos chanos) sebagai media altenatif Agar Nutrien dan menganalisis kemampuannya pada pertumbuhan Escherichia coli dan Staphylococcus aureus.…”

Section: Pendahuluanunclassified

Ability Analysis Of Waste Milkfish (Chanos chanos) As Alternative Medium Of Nutrient Agar On Escherichia coli And Staphylococcus aureus Growth

Gufron¹,

Pestariati²,

Arifin³

2022

medicra

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Waste milkfish got a lot from the residual processed milkfish production of Sidoarjo. The intestines, liver, and kidneys of waste milkfish contain protein, carbohydrates, and fat. The abundant availabilities were usable as a bacterial growth medium, including Nutrient Agar. Nutrient Agar has a high price and is produced by many foreign companies that can trigger a hard availability in laboratories of domestic healthcare, especially in frontier, outermost, and underdeveloped areas. This research aims to analyze the ability of waste milkfish as an alternative medium for Nutrient Agar on the growth of Escherichia coli and Staphylococcus aureus. The ability has been observed by the characteristics and number of bacterial colonies. This research was held in the bacteriology laboratory of the Medical Laboratory Technology Department, Health Polytechnic of Surabaya health ministry. The research type was True-experimental with a post-test-only control group design. Based on the preliminary test results, the waste milkfish mass variations were found in 7 grams, 7.5 grams, 8 grams, 8.5 grams, and 9 grams. Bacteria have been inoculated by the spread plate method, bacterial colony growth has been calculated by the Total Plate Count method. The data were analyzed by the Kruskal-Wallis test with a Sig. value <0.05 that there were differences in the number of Escherichia coli and Staphylococcus aureus colonies in milkfish waste media with various mass. The results showed that the best ability of waste milkfish as an alternative medium for Nutrient Agar on bacterial growth was found in 9 grams mass variation. the average number of Escherichia coli colonies were 186 × 1013 CFU/mL and Staphylococcus aureus colonies were 188 × 1013 CFU/mL.

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Risk Factors for Urinary Tract Infection in Hospitalized Patients

Cited by 7 publications

References 17 publications

Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia

Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Ability Analysis Of Waste Milkfish (Chanos chanos) As Alternative Medium Of Nutrient Agar On Escherichia coli And Staphylococcus aureus Growth

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