Risk factors for the development of complicated appendicitis in adults

Naderan, Mohammad; Babaki, Amir Eslami Shahr; Shoar, Saeed; Mahmoodzadeh, Hashem; Nasiri, Sara; Khorgami, Zhamak

doi:10.5152/ucd.2015.3031

Cited by 24 publications

(37 citation statements)

References 34 publications

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“…Migration of pain was seen as the most common symptom among the patients which was similar to a study by Naderan et al and Iamarino et al 29,30 Other symptoms als reported by these authors were fever and nausea/vomiting. The serum WBC levels in present study was prominently on the patients with perforated appendix rather than in the non-perforated one.…”

Section: Discussionsupporting

confidence: 88%

“…27 There was a preponderance of males in the study compared to the females. Similar results were observed in another study by Drake et al and Naderan et al 28,29 It was suggested by Naderan et al that one of the explanation for the preponderance of the males could be that the women were directed to a gynecologist due to a common symptom of pain in abdomen for many gynecological problems.…”

Section: Discussionsupporting

confidence: 87%

“…Many of the patients were from the lower background, which was observed in the study by Naderan et al29, Ming et al1, Tsai et al 2,29 It was found that in the adult population of the lower economic strata of patients, there was a greater risk of developing complications rather than in the pediatric as well as the upper strata. This was probably the older people preferred a self-treatment or treatment from a local doctor so as to not be a burden to the family.…”

Section: Discussionmentioning

confidence: 91%

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Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Paidipelly

Sangamitra²

2018

Int Surg J

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Background: Acute appendicitis is one of the common conditions observed in the surgery department, which requires an emergency appendectomy with complicated appendicitis including perforated appendicitis is a cause of great concern involving severe morbidity and mortality. To improve our understanding of the sign and symptoms as well as the clinical findings of appendectomy, both in perforated and non-perforated appendicitis, this study was conducted retrospectively on the –patients who attended our hospital.Methods: T The demographic details of 184 the patients in this retrospective study were noted such as age, sex, weight and height, socioeconomic status, the sign and symptoms of the illness at the time of admission, time taken for the surgery to be performed after the admission was noted. All the investigations details such as random blood sugar, complete blood picture, hemoglobin, radiological findings abdominopelvic CT scan where necessary were also noted.Results: Out of the 184 patients admitted to our hospital for appendectomy 22% had perforated appendicitis and 78% had uncomplicated nonperforated appendicitis. The mean age of all the patients in the no perforated group was 30 ± 8.3 and 33±10.2 among the perforated group, with males being more affected than females. The most common symptom among all the patients was migrating pain in the abdomen, followed by anorexia, fever and vomiting. There was a greater time lapse between the onset of symptoms to the admission time in the patients with perforated appendicitis (4.9±1.6 days), compared to the non-perforated cases (2.4±1.8 days), with longer hospital stay and raised WBC counts.Conclusions: Proper education regarding the health and well-being of a patient of any age group should properly be given to the patient and their approach to the hospital at the earliest must be reiterated.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 91%

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Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Paidipelly

Sangamitra²

2018

Int Surg J

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“…Delayed presentation for medical care has traditionally been regarded as a risk factor for complicated appendicitis. 7 , 8 Therefore, this study attempted to evaluate the prevalence of complicated appendicitis during the current outbreak, and to determine the risk factors linked with complicated appendicitis.…”

Section: Introductionmentioning

confidence: 99%

Complicated appendicitis are common during the epidemic period of 2019 novel coronavirus (2019-nCoV)

Gao¹,

Li²,

Zhou³

et al. 2020

Asian Journal of Surgery

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Objectives To assess the prevalence of complicated appendicitis (including gangrene, abscess and perforation) after the outbreak of the 2019-nCoV epidemic and to identify the risk factors associated with complicated appendicitis. Methods Two groups were established in the study consisting of: one group for cases of acute appendicitis before the 2019-nCoV epidemic (before January 1, 2020; pre-epidemic group) and another group for those after the epidemic outbreak (after January 1, 2020; epidemic group). These two groups were compared in terms of demographic and clinical characteristics, prevalence of complicated appendicitis, and treatment intention. A multivariate analysis model using binary logistic regression was constructed. Results A total of 163 patients were included in this study, with 105 in the pre-epidemic group and 58 in the epidemic group. In the epidemic group, the interval from the onset of symptoms to admission was 65.0 h, which is significantly longer than the 17.3 h interval noted in the pre-epidemic group ( P < 0.001). The prevalence of complicated appendicitis after the epidemic outbreak was significantly higher than before the outbreak (51.7% vs. 12.4%, P < 0.001). In addition, the epidemic group had a lower score of patient’s intention to seek treatment than the pre-epidemic group (9.5 ± 2.7 vs. 3.4 ± 2.6, P < 0.001). Based on the multivariate analysis, the risk factors for complicated appendicitis included the time from symptoms onset to admission (OR = 1.075) and the patients’ intention to receive treatment (OR = 0.541). Conclusion Complicated appendicitis was more common in patients with acute appendicitis after the outbreak of the 2019-nCoV epidemic.

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“…In 2016, a study by Naderan et al also found older age, diarrhea, malaise, and right lumber quadrant pain to be associated with perforated appendix. 18 Acute appendicitis is commonly believed to occur as a result of luminal obstruction. This can be due to lymphoid hyperplasia, fecalith, parasite or a malignant or benign stricture at the base.…”

Section: Discussionmentioning

confidence: 99%

Perforated appendicitis: Can it be a bedside diagnosis?

Tariq

Malik

Changeez

et al. 2020

TPMJ

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Appendicitis remains one of the most common causes of acute abdomen worldwide. It presents as a spectrum of disease ranging from an acutely inflamed appendix to a perforated one. Where acutely inflamed can be managed conservatively, a perforated appendix always needs surgery to prevent complications like pelvic abscesses. Bedside diagnosis remains relevant in our setup. Objectives: To determine whether history, clinical examination, and basic laboratory investigations can help in confident bedside diagnosis of perforated appendicitis especially in the absence of sophisticated diagnostic modalities. Study Design: Retrospective Case-control study. Setting: Surgical Unit-1, Holy Family Hospital. Period: Jan 2016 to Dec 2016. Material & Methods: Conducted at Hospital records of patients who underwent open appendectomy in the year 2016 were reviewed. Two groups of 100 patients each were made based on per operative findings. Appendices having macroscopic holes in the base or tip were labeled as perforated. Group A had acutely inflamed appendix and group b had perforated appendix. Patients’ demographic details were taken from hospital admission tickets. Findings of history and examination were retrieved from treating resident and operating surgeon's notes. Data were analyzed through SPSS. Results: Out of 200 patients the total number of males was 102 (51%) and females were 98 (49%). Mean age was 24.13+9.73 in males and 18.7+ 6.4 in females of group A and 26.0+10.1 in males and 20.56+7.53 in females of Group B. Group B showed a significant delay in presentation to emergency after the onset of pain (P = 0.022). Upon history and clinical examination, the presence of anorexia, malaise, generalized abdominal pain, guarding, mass in right iliac fossa were significantly associated with perforation. Whereas gender, fever, vomiting, and dysuria showed no association with perforation. Conclusion: Bedside conventional methods of history taking and examination remain a useful tool in anticipating perforated appendicitis. This helps surgeons in planning incisions and prioritizing patients on heavy operating lists. This remains especially relevant in resource-constrained setups where sophisticated modalities like CT scans are largely unavailable.

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Risk factors for the development of complicated appendicitis in adults

Cited by 24 publications

References 34 publications

Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Complicated appendicitis are common during the epidemic period of 2019 novel coronavirus (2019-nCoV)

Perforated appendicitis: Can it be a bedside diagnosis?

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