Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Paidipelly, Kiran Kumar; Sangamitra,

doi:10.18203/2349-2902.isj20182488

Cited by 3 publications

(4 citation statements)

References 24 publications

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“…The age distribution was similar to findings of Nadir et al, who conducted a similar study in Rawalpindi. 10 The studies conducted by Paidipelly et al, 11 and Patel et al, 12 revealed male dominance as compared to females which was in concordance to our findings.…”

Section: Discussionsupporting

confidence: 91%

Histopathological Evaluationof Appendectomy Specimens in a Tertiary Care Hospital

Noreen

Ghazal²,

Ambreen³

et al. 2022

PAFMJ

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Objective: To find out the histopathological findings in appendectomy specimens, negative appendectomy rate (NAR) and the association of gender and age groups which underwent negative appendectomies in our set up. Study Design: Cross sectional study. Place and Duration of Study: POF Hospital, Wah Cantt, from Jan to Aug 2017. Methodology: The records of 1050 patients were assessed for the relevant clinical history, age, gender and date of their presentation in hospital. The appendectomy specimens were classified as positive specimens which contained fecoliths, worms, granulomatous inflammation, foreign body reaction, mucocele, or appendiceal tumors. All the data were entered and analyzed in SPSS-21. Results: Among the 1050 patients with suspicion of acute appendicitis, 458 (43.6%) were cases of acute appendicitis followed by acute suppurative appendicitis 100 (9.5%) and fecolith 79 (7.5%) in appendiceal lumen. The negative appendectomy rate was calculated as 248 (23.6%). A significant association of normal appendices was found with female gender (p=0.002) and young age group (p=0.02). Conclusion: Acute appendicitis was the most frequent histopathological finding in our study. The negative appendectomy rate was significantly associated with the females of young age.

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Section: Discussionsupporting

confidence: 91%

Histopathological Evaluationof Appendectomy Specimens in a Tertiary Care Hospital

Noreen

Ghazal²,

Ambreen³

et al. 2022

PAFMJ

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“… 17 , Ghag et al . 7 , and Paidipelly et al 15 . The retrocaecal position of the appendix often poses a diagnostic difficulty, both clinically and radiologically, which leads to delayed diagnosis and is thus most commonly associated with appendicular perforation and peritonitis.…”

Section: Discussionmentioning

confidence: 96%

“…The most common symptom in patients with perforated appendicitis was pain in the abdomen (Table 4 ), seen in all patients (100%) followed by vomiting (64.3%), and fever (38.9%), thus correlating with the findings observed by Paidipelly et al . 15 , Tantarattanapong et al . 16 , and Pramod and Prakashkumar 10 .…”

Section: Discussionmentioning

confidence: 99%

Study of outcomes of perforated appendicitis in adults: a prospective cohort study

Potey

Kandi

Jadhav

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction: Acute appendicitis remains the most common general surgical emergency seen in most hospitals and the most common cause of acute abdomen requiring surgical intervention. Aim: The aim was to study the intraoperative features and postoperative outcomes of appendicular perforation in adults. Objectives: First, to study the incidence, clinical presentation, and complications of perforated appendicitis in a tertiary care hospital. Second, to study morbidity and mortality in an operated case of perforated appendicitis. Materials and Methods: This prospective observational study was conducted at a tertiary care centre in a government setup from August 2017 to July 2019. Data were collected from patients ( N =126) who had an intraoperative finding of perforated appendicitis. The inclusion criteria are as follows: patients over the age of 12 with a perforated appendix, as well as any patients with intraoperative findings like perforated appendicitis, gangrenous perforated appendicitis, or a disintegrated appendix. The exclusion criteria are as follows: all patients with appendicitis below 12 years of age with perforated appendicitis; all patients with appendicitis with intraoperative findings of acute nonperforated appendicitis; and all patients with intraoperative findings of an appendicular lump or mass. Results: Perforation was found in 13.8% of the cases of acute appendicitis in this study. With a mean age of 32.5 years, the most common age of presentation in perforated appendicitis was 21–30 years. The most prevalent presenting symptom in all patients (100%) was abdominal pain, followed by vomiting (64.3%) and fever (38.9%). Patients with perforated appendicitis had a 72.2% complication rate. Peritoneal pollution of more than 150 ml was linked to a 100% increase in morbidity and mortality (54.5%). The mean duration of the hospital stay in patients with a perforated appendix was 7.28±5 days. Surgical site infection (42%) was the most common early complication, followed by wound dehiscence (16.6%), intestinal obstruction (1.6%), and faecal fistula (1.6%). The most common late complications were intestinal obstruction (2.4%), intra-abdominal abscess (1.6%), and incisional hernia (1.6%). The mortality rate in patients with perforated appendicitis was 4.8%. Conclusion: To conclude, prehospital delay was an important factor contributing to appendicular perforation and leading to adverse outcomes. A higher rate of morbidity and prolonged duration of hospital stay were seen in patients with delayed presentation, with features of generalised peritonitis and perforation of the base of the appendix. Delayed presentations in as elderly population with underlying co-morbid conditions associated with severe peritoneal contamination were associated with higher mortality (26%) in perforated appendicitis. Conventional surgery and open procedu...

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“…However, they are expensive and sometimes inaccessible [7,8]. Several scoring systems have been developed to help in the diagnosis of appendicular perforation such as Alvarado and modified Alvarado scoring system; patients with normal leukocyte count and neutrophil count are highly unlikely to have appendicular perforation; and the purpose of our study is to find the usefulness of above in our setup [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

A Study of Clinicopathological Profile in Patients of Appendicular Perforation

NIVEDITA K,

MOHAMMED FAIZUL VIQHAS K,

Alam

et al. 2023

Asian J Pharm Clin Res

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Introduction: Appendicular perforation is one of the most common surgical emergencies. The diagnosis of appendicular perforation is based on clinical history, examination combined with investigation. Hb, total leukocyte count (TLC), and neutrophil USG CT help in confirming the diagnosis. Methods: A prospective study was conducted on patient coming with appendicular perforation, at a tertiary care center. Included subject underwent a through physical and clinical evaluation. Data were collected in performa and statistical analysis was done by applying the appropriate test. Results: Among 100 cases of operated appendectomy, great number of patients belonged to 11–20 years (40%) with male predominance (72%). Among all, 90% were diagnosed as histopathological examination positive (appendicular perforation). Sixty-nine percent (69%) patients were C-reactive protein (CRP) positive. Increased TLC in 70% of patients and raised neutrophilia in 54% of patients was observed. Out of 100 patients, 86% were USG positive and retrocecal appendix was the most common position. Tenderness at RIF was the most common sign present (100%). Rovsing’s sign was present in 25% cases while 15% cases were noted with obturator test. Majority of them (70%) had score of >7 and were diagnosed as modified Alvarado-positive cases. Conclusion: In our study, the combination of CRP, TLC, and neutrophil count has PPV of 100% which signifies their greater diagnostic accuracy in early diagnosis of acute appendicitis while the NPV after combining this test is 100% which signifies negative appendectomy can be decreased, if appendectomy is avoided in cases where TLC, CRP, and NC are normal.

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Risk factors of acute and perforated appendicitis in a semi-rural population: a retrospective study

Cited by 3 publications

References 24 publications

Histopathological Evaluationof Appendectomy Specimens in a Tertiary Care Hospital

Histopathological Evaluationof Appendectomy Specimens in a Tertiary Care Hospital

Study of outcomes of perforated appendicitis in adults: a prospective cohort study

A Study of Clinicopathological Profile in Patients of Appendicular Perforation

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