Risk Factors for the Development of Hypothyroidism After Hemithyroidectomy

Abstract

Setting: A tertiary care academic medical center. Patients: The study included 90 patients who underwent a hemithyroidectomy from 1999 to 2004. Main Outcome Measures: Hypothyroidism was defined as a serum thyrotropin level greater than 6.0 mIU/L at least 8 weeks after hemithyroidectomy. All patients were analyzed for age, sex, surgical indications, preoperative and postoperative thyrotropin levels, weight of resected specimen, final pathologic analysis, and length of followup. Multivariate analysis was performed to identify multiple risk factors for the development of hypothyroidism. Results: The final pathologic analysis demonstrated 49 follicular adenomas, 17 cases of Hashimoto thyroiditis, 10 multinodular goiters, and 14 other abnormalities. The overall incidence of the development of hypothyroid

Minimally invasive thyroid nodulectomy reduces post‐operative hypothyroidism when compared with thyroid lobectomy

“…Of the four patients in the nodulectomy group with elevated post‐operative TSH, two had formal histology consistent with Hashimoto's thyroiditis. Previously reported series have found a similar relationship between lymphocytic thyroiditis, Hashimoto's thyroiditis, detectable autoantibodies and an increased rate of hypothyroidism . In the lobectomy group, our result of 22.1% patients becoming hypothyroid following surgery is also consistent with the results of previous series.…”

Hemithyroidectomy for benign thyroid disease: who needs follow‐up for hypothyroidism?

“…Previous studies demonstrate an incidence of hypothyroidism ranging from 5% to 41.9% 1–10 . Our figures are approximately midway and agree favourably with other studies.…”

“…Previous studies demonstrate an incidence of hypothyroidism ranging from 5% to 41.9%. [1][2][3][4][5][6][7][8][9][10] Our figures are approximately midway and agree favourably with other studies. The disparity of results seen in other studies is partly because of lack of consensus in the definition of hypothyroidism used and because of the differences in the length of follow up.…”

The Incidence of Hypothyroidism Following Hemithyroidectomy in a Tertiary Academic Center in Saudi Arabia

“…In our study, 17 (43.59%) patients developed hypothyroidism after hemithyroidectomy, comparable with the percentages reported in other studies [4,8,12,13]. Hemithyroidectomy can result in the potentially disabling consequence of hypothyroidism.…”