Risk factors for surgical site infections among 1,772 patients operated on for lumbar disc herniation: a multicentre observational registry-based study

Habiba, Samer; Nygaard, Øystein P.; Brox, Jens Ivar; Hellum, Christian; Austevoll, Ivar Magne

doi:10.1007/s00701-017-3184-2

Cited by 12 publications

(15 citation statements)

References 25 publications

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“…Six studies investigated the relationship between obesity and postoperative SSI. 30 – 32 , 35 , 36 , 43 The pooled result showed that obesity patients had a 2.87-fold increased risk of SSI than those of normal weight (RR 2.87, 95% CI 1.62–5.09; P <0.001). This indicated that obesity was a significant risk for SSI.…”

Section: Resultsmentioning

confidence: 98%

“…Nine studies investigated the relationship between current smoking and postoperative SSI. 28 , 30 – 32 , 34 , 35 , 37 , 39 , 43 Pooled estimates showed that current smokers had a comparable rate of postoperative SSI than nonsmokers (RR 0.89, 95% CI 0.75–1.06; P =0.178; Figure 5 ). This indicated that current smoking did not increase the risk of postoperative SSI in patients with lumbar spine surgery.…”

Section: Resultsmentioning

confidence: 99%

“…The total sample size was 13,393, of which 704 were in the SSI group and 12,689 the non-SSI group. Among these studies, nine 28 , 31 , 32 , 35 – 37 , 40 , 41 , 43 were conducted in the US, two in China, 33 , 42 and one each in South Korea, 29 Norway, 30 Japan, 34 Brazil, 38 and the Netherlands. 39 Most studies were performed with a retrospective case–control design, except three, which were prospective 34 , 38 or retrospective 41 cohort design.…”

Section: Resultsmentioning

confidence: 99%

“…Four studies investigated the relationship between American Society of Anesthesiologists (ASA) grade and postoperative SSI. 28 , 30 , 34 , 43 Pooled estimates suggested that patients with ASA grade >2 had a similar rate of postoperative SSI compared with those with ASA grade 1–2 (RR 2.63, 95% CI 0.84–8.27; P =0.098). This demonstrated that ASA grade >2 did not increase the risk of postoperative SSI.…”

Section: Resultsmentioning

confidence: 99%

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Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis

Zhang¹,

Li²

2018

TCRM

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ObjectiveTo identify risk factors for surgical site infection (SSI) in patients who had undergone lumbar spinal surgery.MethodsStudies published in PubMed, Web of Science, and Embase were systematically reviewed to determine risk factors for SSI following lumbar spinal surgery. Results are expressed as risk ratios (RRs) with 95% CIs and weighted mean difference (WMD) with 95% CI. A fixed-effect or random-effect model was used to pool the estimates according to heterogeneity among the studies included.ResultsSixteen studies involving 13,393 patients were included in this meta-analysis. Pooled estimates suggested that diabetes (RR 2.19, 95% CI 1.43–3.36; P<0.001), obesity (RR 2.87, 95% CI 1.62–5.09; P<0.001), BMI (WMD 1.32 kg/m2, 95% CI 0.39–2.25; P=0.006), prolonged operating time (WMD 24.96 minutes, 95% CI 14.77–35.15; P<0.001), prolonged hospital stay (WMD 2.07 days, 95% CI 0.28–3.87; P=0.024), hypertension (RR 1.28, 95% CI 1.08–1.52; P=0.005), and previous surgery (RR 2.06, 95% CI 1.39–3.06; P<0.001) were independent risk factors for SSI in patients who had undergone lumbar spine surgery. Current smoking (RR 0.89, 95% CI 0.75–1.06; P=0.178), American Society of Anesthesiologists grade >2 (RR 2.63, 95% CI 0.84–8.27; P=0.098), increased age (WMD 1.43 years, 95% CI −1.15 to 4.02; P=0.278), COPD (RR 1.21, 95% CI 0.68–2.17; P=0.521), cardiovascular disease (RR 1.63, 95% CI 0.40–6.70; P=0.495), rheumatoid arthritis (RR 1.76, 95% CI 0.53–5.90; P=0.359), and osteoporosis (RR 1.91, 95% CI 0.79–4.63; P=0.152) were not risk factors for postoperative SSI.ConclusionOur results identified several important factors that increased the risk of postoperative SSI. Knowing these risk factors, surgeons could adequately analyze and evaluate risk factors in patients and then develop prevention measurements to reduce the rate of SSI.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis

Zhang¹,

Li²

2018

TCRM

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“…Predictors of infection following microdiscectomy include absence of prophylactic antibiotic dosing and duration of surgery > 68 min [90]. Interestingly, one study did not find that preoperative lumbar epidural CSI increased infection risk [91].…”

Section: Open Discectomymentioning

confidence: 99%

Lumbar Disc Herniation

Amin

Andrade

Neuman³

2017

Curr Rev Musculoskelet Med

229

202

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Purpose of Review Substantial advancements have been made in the cause, diagnosis, imaging, and treatment options available for patients with lumbar disc herniation (LDH). We examined the current evidence and highlight the concepts on the frontline of discovery in LDH. Recent Findings There are a myriad of novel etiologies of LDH detailed in recent literature including inflammatory factors and infectious microbes. In the clinical setting, recent data focuses on improvements in computer tomography as a diagnostic tool and non-traditional injection options including tumor necrosis alpha inhibitors and platelet-rich plasma. Operative treatment outcomes have focused on minimally invasive endoscopic approaches and demonstrated robust 5-year post-operative outcomes. Summary Advances in the molecular etiology of LDH will continue to drive novel treatment options. The role of endoscopic treatment for LDH will continue to evolve. Further research into10-year outcomes will be necessary as this surgical approach continues to gain widespread popularity.

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Pyogenic Infections of the CNS 3

Roux

Still

Zanello

et al. 2020

Infections of the Central Nervous System

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Risk factors for surgical site infections among 1,772 patients operated on for lumbar disc herniation: a multicentre observational registry-based study

Abstract: In summary, this study clearly lends support to the use of PAT in surgery for lumbar disc herniation. Senior surgeons assisting inexperienced colleagues to avoid prolonged duration of surgery could also reduce the occurrence of SSI.

Cited by 12 publications

References 25 publications

Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis

Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis

Lumbar Disc Herniation

Pyogenic Infections of the CNS 3

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