Lumbar Disc Herniation

Amin, Raj M.; Andrade, Nicholas S.; Neuman, Brian J.

doi:10.1007/s12178-017-9441-4

Cited by 205 publications

(207 citation statements)

References 104 publications

(84 reference statements)

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“…On an annual basis 1% of the United States adult population will be afflicted by lumbar disc herniation, affecting an estimated 2.8 million people each year . Contemporary treatment options involve physical therapy, corticosteroid injection, and nonsteroidal anti‐inflammatory drug administration, which is able to alleviate symptoms for a large fraction of patients . Alternatively, herniated disc material can be excised to alleviate inflammation and potentially decompress neighboring nerves.…”

Section: Introductionmentioning

confidence: 99%

Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model

et al. 2019

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In recent years, studies have explored novel approaches for cell transplantation to enable annulus fibrosus (AF) regeneration of the intervertebral disc in particular for lumbar disc herniation. Nevertheless, successful engraftment of cells is structurally challenging, and no definitive method has yet been established. This study investigated the potential of cell sheet technology to facilitate cell engraftment for AF repair. AF injury was induced by a 1 × 1 mm defect in rat tails after which AF cell sheets were transplanted. Its regenerative effects were compared to a nondegenerated and degeneration only conditions. Degenerative changes of the entire intervertebral disc were examined by disc height measurements, histology, and immunohistochemistry for 4‐, 8‐, and 12‐weeks post‐transplantation. Cell engraftment was confirmed by tracing PKH26 fluorescent dyed AF cells. In the transplant group, disc degeneration was significantly suppressed after 4, 8, and 12 weeks when compared with the degenerative group, as indicated by histological scoring and DHI observations. At 2 and 4 weeks after transplant, PKH26 positive cells could be detected in defect region and surrounding AF. The results suggest cell engraftment into AF tissue could be established by the cell sheet technology without additional scaffolding or adhesives. In short, AF cell sheets appear to be an effective and accessible tool for AF repair and to support intervertebral disc regeneration.

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Section: Introductionmentioning

confidence: 99%

Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model

et al. 2019

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“…Bel ağrısının en sık nedenlerinden birisi lomber disk hernisidir. Lomber disk hernisi kalıcı fonksiyonel kayıplara ve iş gücü kaybına neden olan en önemli sağlık sorunlarından biridir (1,2). Lomber disk hernisi 30-50 yaş erkeklerde ve sıklıkla lomber 4-5 ya da lomber 5-sakral 1 vertebraları arasında görülür (3,4,5).…”

Section: Introductionunclassified

Determination of Healthy Lifestyle Behaviors and Self-Care Agency of Patients with Lumbar Disc Hernia

Dönmez¹,

Gıersbergen²,

Başli

et al. 2019

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi

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Öz Amaç: Tanımlayıcı ve kesitsel tipte olan çalışma, lomber disk hernisi olan hastaların sağlıklı yaşam biçimi davranışlarını ve öz-bakım gücünü incelemek amacıyla yapıldı. Yöntem: Bir üniversite hastanesinin Beyin ve Sinir Cerrahisi Anabilim Dalı'nda lomber disk hernisi tanısı ile yatan 240 hasta çalışmaya dahil edildi. Araştırmanın verileri Kişisel Bilgi Formu, Sağlıklı Yaşam Biçimi Davranışları Ölçeği II (SYBDÖ) ve Öz-Bakım Gücü Ölçeği (ÖBGÖ) kullanılarak toplandı. Verilerin analizinde PASW 18 paket programı kullanıldı. Bulgular: Araştırmaya katılan hastaların yaş ortalaması 50.88±14.05, %73.8'i kadındı. Katılımcıların lomber disk hernisi tanısı konulma zamanı ortalama 5.8 yıldı ve %39.02'sinin bel ağrısı şikayeti ile hastaneye başvurduğu saptandı. Lomber disk hernili bireylerin Sağlıklı Yaşam Biçimi Davranışları Ölçeği puan ortalaması 125.09±21.05 ve Öz-Bakım Gücü Ölçeği puan ortalaması 73.32±24.36 olarak belirlendi. Yaş, beden kitle indeksi, sosyoekonomik durum ve kronik hastalık varlığının sağlıklı yaşam biçimi davranışlarını etkilediği saptandı. Kırk yaşın altında, çalışan ve lomber disk hernisi ile ilgili önceden tedavi gören hastaların öz-bakım gücünün daha yüksek olduğu saptandı. Sonuç: Hastaların öz-bakım gücünün ve sağlıklı yaşam biçimi davranışlarının orta düzeyde olduğu belirlendi. Lomber disk hernisinin fiziksel aktivite seviyelerini olumsuz yönde etkilediği saptandı.Anahtar kelimeler: lomber disk hernisi, sağlık yaşam biçimi, öz-bakım Abstract Aim: The descriptive and cross-sectional study was conducted to investigate the healthy lifestyle behaviors and self-care agency of patients with lumbar disc herniation.Methods: A total of 240 patients with lumbar disc herniation were included in the study in the Department of Brain and Nerve Surgery of a university hospital. The data of the study were collected by using personal information form, Health Promoting Lifestyle Profile Scale II and Self-Care Agency Scale. PASW 18 package program was used for statistical analysis. Results:The mean age of the patients was 50.88 ± 14.05 years and 73.8% of the patients were female. The mean time of diagnosis of lumbar disc herniation was 5.8 years and 39.02% of the participants were admitted to the hospital with low back pain. The mean score of Health Promoting Lifestyle Profile Scale II of the patients with lumbar disc herniation was 125.09 ± 21.05 and the mean score of Self-Care Agency Scale was 73.32 ± 24.36. Age, body mass index, socioeconomic status and presence of chronic disease were found to affect healthy lifestyle behaviors. Patients who were under 40 years of age and who were previously treated for lumbar disc herniation had higher self-care agency.Conclusion: It was determined that the self-care agency and healthy lifestyle behaviors of the patients were moderate. It was observed that lumbar disc herniation had a negative effect on physical activity levels.

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“…Disc herniation occurs mainly between the fourth and fifth decades of life (mean age of 37 years), although it has been described in all ages (4). Due to the large axial load to which it is exposed, the nucleus pulposus has a constant tendency to move and expand from the center of the disk to its periphery (5,6). Local displacement of the contents of the dicus beyond the boundary of the intervertebral space is defined as the discus hernia (5,6).…”

Section: Introductionmentioning

confidence: 99%

“…Due to the large axial load to which it is exposed, the nucleus pulposus has a constant tendency to move and expand from the center of the disk to its periphery (5,6). Local displacement of the contents of the dicus beyond the boundary of the intervertebral space is defined as the discus hernia (5,6). The disc herniation can be protrusion, prolapse or extrusion and sequestration -dislocation of disc contents in various directions (5,6).…”

Section: Introductionmentioning

confidence: 99%

Lumbar-load analysis of a soldier while carrying the heavy loads

Burak

Veljović²,

Begić³

et al. 2019

PEN

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Background: The aim of the article was to create an appropriate computer model based on the real status of the mortar operator's workplace and to analyze the workplace. After that, for any possible exceedances from the aspect of the organism's load and safety, the aim is to redesign the workplace and bring it within the limits of the permissible load, and therefore the required safety. The aim is also to identify the characteristic work movements performed by the soldier and to carry out an ergonomic analysis of the soldier's efforts and to propose appropriate improvements. Methods: The analysis is performed on a total of 20 soldiers, from which is determined an average model of the following characteristics: 180 cm in height and 85 kg in weight. The task is to take a mine from the shell containing the mines, then transfer it to the mortar and fill the mortar barrel. The weight of the 120 mm mortar grenade is 14.8 kg. The average soldier is 26 years old and his military exercise lasts 4 hours. The CATIA software package (Dassault Systèmes, Vélizy-Villacoublay, France) is used for analysis. By knowing the anthropometric and work environment data, with ergonomic design and analysis, the following analyses were made: biomechanical analysis, rapid upper limb assessment (RULA) and carry analysis (option from CATIA software). Results: The proposed modification of the position resulted in a decrease in the L4/L5 torque from 316 Nm to 154 Nm along with decreasing of the compression force on the L4/ L5 from 5,779 N to 3038 N (the compression force allowed is 3,400 N), and while the RULA analysis is from the red color position 1 (score 7; maximum load requiring rapid repositioning of such position), revised final score 4 made in yellow (a solution acceptable for this work place). Conclusions: By ergonomic analysis, obtained proposal will lead to less chance of injury, prevention of burn out syndrome, fewer chances of illness, decreasing the fatigue, greater safety, less energy spent and better preparedness for all necessary tasks.

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Lumbar Disc Herniation

Cited by 205 publications

References 104 publications

Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model

Annulus fibrosus cell sheets limit disc degeneration in a rat annulus fibrosus injury model

Determination of Healthy Lifestyle Behaviors and Self-Care Agency of Patients with Lumbar Disc Hernia

Lumbar-load analysis of a soldier while carrying the heavy loads

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