Risk Factors for Premature Atherosclerosis

Abstract

the difference in the prevalence of the different risk factors between the two groups suggests that either certain risk factors are more likely to cause premature atherosclerosis, or that other risk factors must be present in addition to the known risk factors in order to induce premature atherosclerosis.

Antineutrophil cytoplasmatic antibodies in patients with premature atherosclerosis: prevalence and association with risk factors

“…In conclusion, autoimmunity to myeloid granules as reflected by ANCA does not seem to be of major importance in patients with premature atherosclerosis. Our data confirm, however, earlier reports that patients with premature atherosclerosis are extensively exposed to risk factors such as dyslipidaemia, smoking, hypertension, a positive family history and hyperhomocysteinaemia [5, 6, 19].…”

“…The aim of this single centre cross‐sectional study was to establish the significance of ANCA in patients with premature atherosclerosis. The majority of our patients with premature atherosclerosis was exposed to a large number of cardiovascular risk factors as reported previously [6, 19]. In addition, there is ample evidence that autoimmune processes are involved in the development of atherosclerosis as well [20, 21].…”

“…This is known as premature atherosclerosis. Why these patients suffer from premature atherosclerosis is not known, but it is evident that most patients are more exposed to multiple established risk factors as compared with their controls [5,6].…”

Severe Preeclampsia is Associated with a Positive Family History of Hypertension and Hypercholesterolemia

“…Angina pectoris, myocardial infarction, cerebrovascular accident, transient ischemic attack, and intermittent claudication were considered as cardiovascular disease. A family history of cardiovascular disease was defined as one or more first-degree relatives with cardiovascular disease before the age of 60 years (17).…”

“…Familial tendency, present in preeclampsia as well as in cardiovascular disease (16,17), may be considered as another joint risk factor. Therefore, women with a positive family history of cardiovascular disease may have a higher risk to develop preeclampsia due to the underlying disorders as mentioned above.…”