Risk factors for Peyronie's disease: a case‐control study

Abstract

RESULTSFrom the multivariate logistic regression analysis the risk factors for PD were: a history of genital and/or perineal injuries, transurethral prostatectomy, cystoscopy, diabetes mellitus, hypertension, lipoma, propranolol in therapy, Dupuytren's contracture in the medical history, ever having smoked, alcohol consumption, fibromatous lesions of the genital tract of the partner, and surgical intervention on the genital tract of the partner. CONCLUSIONThe results of the present study are in line with the hypothesis that, in addition to genetic predisposition, trauma of the penis and systemic vascular diseases are risk factors for PD. Smoking and alcohol consumption also seem to have some role in the development of the disease.

The association between Peyronie's and Dupuytren's disease

“…Previous reports concerning coexisting DD in patients presenting with PD show ranges varying from 0.01 to 58.8%, a positive family history for PD in 1-4% and a positive family history for DD in 9.8% (Table 2). 5,9,[14][15][16][17][18][19][20][21][22][23][24] The series from the UK, Italy, Australia and Serbia show the highest percentage of PD patients with coexisting DD. 9,15,17,19,24 The two reports focusing on PD patients o40 years show a lower percentage of coexisting DD.…”

“…13 The literature concerning coexisting DD in patients presenting with PD shows wide ranges varying from 0.01 to 58.8%. 5,9,[14][15][16][17][18][19][20][21][22][23][24] The aim of this study is to investigate the coexistence of DD in a consecutive series of patients with PD and their clinical characteristics, presenting at the outpatient urological clinic of the University Medical Centre Groningen, The Netherlands.…”

Relationship between penile fracture and Peyronie's disease: a prospective study

“…17 On the other hand, in two separate controlled studies including 82 and 134 patients with PD, respectively, none of the cases had PF history. 24,25 Similarly, no history of PF was reported in a retrospective study on 307 patients with PD. 26 In all of these clinical studies, Peyronie's plaque was diagnosed with medical history and physical examination.…”

Alcohol and men's health

“…13 It has been hypothesised that, like erectile dysfunction, the relationship observed between Peyronie's disease and alcohol use is largely through cardiac pathways (particularly hypertension and hyperlipidaemia).…”