Risk factors for latex allergy in patients with spina bifida

Michael, T; Niggemann, B.; Moers, A von; Seidel, Ulrich; Wahn, Ulrich; Scheffner, D.

doi:10.1111/j.1365-2222.1996.tb00629.x

Cited by 94 publications

(40 citation statements)

References 19 publications

(18 reference statements)

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“…Six patients (8%) have had a severe life-threatening reaction to latex. As reported by others, the risk of becoming latex allergic increases as the number of surgical procedures increases [18, 19, 20]. Those study patients allergic to latex have had twice as many shunt revisions as those without a latex allergy.…”

Section: Discussionmentioning

confidence: 61%

Spina Bifida Outcome: A 25-Year Prospective

Bowman

McLone

Grant³

et al. 2001

Pediatr Neurosurg

628

493

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Background: Open spina bifida is the most complex congenital abnormality compatible with long-term survival. This report outlines the 20- to 25-year outcome for our original cohort of patients with a myelomeningocele treated in a nonselective, prospective manner. Methods: Of the initial 118 children, 71 patients were available for our most recent review. Nineteen patients have been lost to follow-up and 28 patients have died. Data were collected on: motor level, shunt status, education/employment, seizure history, mobility, bladder/bowel continence, tethered cord, scoliosis, latex allergy, posterior cervical decompression, tracheostomy and/or gastrostomy tube. Results: Mortality (24%) continues to climb into young adulthood. Eighty-six percent of the cohort have cerebrospinal fluid diversion, with 95% having undergone at least one shunt revision. Thirty-two percent have undergone a tethered cord release, with 97% having an improvement or stabilization in their preoperative symptoms. Forty-nine percent have scoliosis, with 43% eventually requiring a spinal fusion. Sixteen patients (23%) have had at least one seizure. Eighty-five percent are attending or have graduated from high school and/or college. More than 80% of young adults have social bladder continence. Approximately 1/3 of patients are allergic to latex, with 6 patients having experienced a life-threatening reaction. Conclusion: At least 75% of children born with a myelomeningocele can be expected to reach their early adult years. Late deterioration is common. One of the greatest challenges in medicine today is establishing a network of care for these adults with spina bifida.

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Section: Discussionmentioning

confidence: 61%

Spina Bifida Outcome: A 25-Year Prospective

Bowman

McLone

Grant³

et al. 2001

Pediatr Neurosurg

628

493

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“…On the other hand, sensitization to natural latex allergens indicating the risk of clinical relevant latex allergies can be investigated by determination of latex-specific IgE in sera. Serological determination of latex-specific IgE published so far indicated positive results in 37–56% of the patients with myelomeningoceles [4, 12, 13]. In our series, 5 out of 40 (12.5%) children, from whom a completed questionnaire was obtained, had a history of latex-related allergic reactions, while 9 out of 31 (29%) patients, in whom a serological screening was possible, showed elevated latex-specific IgE.…”

Section: Discussionmentioning

confidence: 71%

Comparison of Questionnaire-Based and Serological Screening for Natural Latex Allergy in Children with Neurogenic Bladder Dysfunction

Zöller¹,

Thermann²,

Conrad

et al. 1998

European Urology

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“…health care workers or children with spina bifida (SB) [1, 2]. In SB patients, the rate of latex sensitization is 29–72% [3, 4, 5, 6]. It still remains to be clarified whether repeated early exposure or possibly a genetic predisposition represents the major factor for sensitization [6].…”

Section: Introductionmentioning

confidence: 99%