Risk factors for late mortality after endovascular repair of the thoracic aorta

Chung, Jayer; Corriere, Matthew A.; Veeraswamy, Ravi K.; Kasirajan, Karthikeshwar; Milner, Ross; Dodson, Thomas F.; Salam, Atef A.; Chaikof, Elliot L.

doi:10.1016/j.jvs.2010.04.059

Cited by 41 publications

(43 citation statements)

References 20 publications

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“…Moreover, in a previous study, inflammatory cell activity in the aortic wall that was determined by positron emission tomography/CT was found to be higher in patients with severe clinical symptoms than in asymptomatic and stable patients (19). On the other hand, systemic inflammatory markers, such as leukocytosis and CRP, were also reported to be independently associated with higher in-hospital and long-term mortality in aortic dissection (7)(8)(9)(10)20,21). These inflammatory markers exhibit different time courses in their changes in acutephase reactions and between acute and chronic aortic diseases, are associated with a poor prognosis, and remain elevated even after repair of the dissection (6).…”

Section: Discussionmentioning

confidence: 97%

Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection

Lafçı¹,

Çiçek²,

Uzun³

et al. 2014

Turk J Med Sci

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vitro, the amino acids glutamic acid, aspartic acid, alanine, glutamine, proline, serine, and arginine induced rooting of explants in the presence of a-naphthalene acetic acid (Kamada and Harada 1979). Furthermore, it was found that while proline (10-200 mg L -1 ) increased the rooting percentage and number of roots per rooted explant of sweet cherry (Prunus avium L.) and sour cherry (Prunus cerasus L.), the root length was reduced (Baraldi et al. 1988).The different forms of nitrogen as well as its proportion can influence a number of factors in various in vitro cultures, such as cell division, the growth and development of somatic embryos, chlorophyll content, ribulose-1, 5-bisphosphate carboxylase/oxygenase activity, the electron transport rate, the photosynthetic rate, fresh mass, soluble protein concentration, and the osmotic pressure of the cell sap (Mashayekhi-Nezamabadi 2000). It has been reported that reduced nitrogen forms, particularly amides and amino acids, can improve cell proliferation, as well as regeneration in specific genotypes (Vasudevan et al. 2004).Methionine, a sulfur-containing amino acid, is a precursor of ethylene biosynthesis in plant tissues (Yang 1985). Besides its function as a protein constituent and its central role in the initiation of mRNA translation, methionine indirectly regulates a range of cellular processes as the precursor of S-adenosylmethionine (SAM) (Amir et al. 2002). Not only is SAM the primary biological methyl-group donor, but it is also the precursor of plant metabolites, including ethylene, polyamines, vitamin B 1 , and the iron chelator mugineic acid (Sun Abstract: In the present study, the effects of indole-3-butyric acid (IBA) alone and in combination with L-methionine were investigated on the morphogenic and biochemical responses in the shoot tip explants of the cherry rootstocks CAB-6P (Prunus cerasus L.) and Gisela 6 (Prunus cerasus × Prunus canescens). The best results for roots, regarding their number and the fresh and dry weight, were obtained with 2 mg L -1 IBA in both rootstocks. Maximum rooting percentage was with the combination of 2 mg L -1 IBA and 0.5 mg L -1 L-methionine. Root length was greatest in the control plants. L-methionine had an inhibitory effect on the leaf chlorophyll content of the CAB-6P rootstock and no effect in Gisela 6. L-methionine with the lowest IBA concentration (0.5 mg L -1 ) exhibited elevated levels of proline in the roots of the CAB-6P rootstock and depleted levels in Gisela 6. For the Gisela 6 rootstock, the leaf carbohydrate concentration was highest with 2 mg L -1 of IBA, whereas in the roots it was highest in the control. For the CAB-6P rootstock, the leaf carbohydrate concentration was not influenced by IBA with L-methionine, whereas the highest carbohydrate concentration in the roots was with the combinations of 0.5 mg L -1 IBA and 1 and 2 mg L -1 L-methionine. Taking into account the different parameters examined, it appears that chlorophyll and carbohydrates are the most accurate biochemical markers of the rooting ...

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Section: Discussionmentioning

confidence: 97%

Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection

Lafçı¹,

Çiçek²,

Uzun³

et al. 2014

Turk J Med Sci

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show abstract

“…Neutrophilia is the product of neutrophil demargination, delayed apoptosis and stimulation of stem cells by interleukin 6 (IL-6) and granulocyte colony stimulating factors (G-CSF). Sudden neutrophilia could be a representative of acute on chronic inflammatory response as neutrophils encourage plaque [24]. Recent literature suggests low lymphocyte to be associated with poor outcome in patients with cardiac pathology (Ischemic heart disease) [23].…”

Section: Discussionmentioning

confidence: 99%

Neutrophil to lymphocyte ratio (NLR) of five predicts 30-day morbidity in ruptured abdominal aortic aneurysms (rAAA): A retrospective cohort study

Kordzadeh

Malietzis

Browne

et al. 2015

International Journal of Surgery

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“…Although efficacy has been demonstrated in symptomatic type B dissection and PAU, there are very little data exploring TEVAR use with IMH without PAU. [42][43][44][45][46] Intuitively, TEVAR use for AD and PAU makes sense as an endograft is excluding an intimal defect and can thrombose a false lumen. However, in the case with IMH, neither is there an intimal defect to exclude nor is there a false lumen to be thrombosed by the radial pressure of the endograft.…”

Section: Type B Imh Management and Outcomesmentioning

confidence: 99%

Current Understandings and Approach to the Management of Aortic Intramural Hematomas

Goldberg

Kim²,

Sundt

2014

Seminars in Thoracic and Cardiovascular Surgery

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Risk factors for late mortality after endovascular repair of the thoracic aorta

Abstract: Preoperative leukocytosis, aneurysm diameter, and concurrent debranching independently predict late mortality irrespective of clinical presentation and may assist in risk stratification.

Cited by 41 publications

References 20 publications

Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection

Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection

Neutrophil to lymphocyte ratio (NLR) of five predicts 30-day morbidity in ruptured abdominal aortic aneurysms (rAAA): A retrospective cohort study

Current Understandings and Approach to the Management of Aortic Intramural Hematomas

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