Neutrophil to lymphocyte ratio (NLR) of five predicts 30-day morbidity in ruptured abdominal aortic aneurysms (rAAA): A retrospective cohort study

Kordzadeh, Ali; Malietzis, George; Browne, Tom; Prionidis, Ioannis; Panayiotopoulos, Y.P.

doi:10.1016/j.ijsu.2015.01.013

Cited by 39 publications

(38 citation statements)

References 21 publications

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“…Previous studies focused on the association between NLR value and poor clinical outcomes of type A aortic dissection or severe aortic events after TEVAR or open surgery. 17,18 In our study, we found signi cant difference of early outcomes between the high NLR group and low NLR group (adverse events, 17.3% vs. 5.4%, P = 0.005) despite that systemic in ammatory response of uTBAD is relatively lower than complicated aortic dissection or type A aortic dissection considering the lesion and comorbidities.…”

Section: Discussionmentioning

confidence: 54%

Elevated Preoperative Neutrophil-to-lymphocyte Ratio Predicts Early Adverse Outcomes in Uncomplicated Type B Aortic Dissection Undergoing TEVAR

Zhu

Zhang

Liang

et al. 2020

Preprint

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Background: Thoracic aortic endovascular repair (TEVAR) of uncomplicated type B aortic dissection (uTBAD) has favorable long-term outcomes but higher early adverse events compared with the optimal medical treatment. Recently, clinical evidence concerning vascular surgery indicates that elevated preoperative systemic inflammatory response predicts adverse clinical events. The aim of our study was to evaluate the relationship between preoperative neutrophil lymphocyte ratio (NLR) and early outcomes of (uTBAD) patients undergoing (TEVAR). Results: 216 patients diagnosed with uTBAD were included in this retrospective study between January 2015 and December 2018. The median (IQR) follow-up period was 21 (15-33) months. An early adverse event was defined as occurring within 2 years after the procedure. Median patient age was 60 (IQR, 48-68) years and 78.7% were male. Early adverse events occurred in 24 patients (11.3%). In the multivariable analysis, preoperative NLR (HR per SD, 1.10; 95% CI, 1.03-1.18; P = 0.003) was associated with 2-year adverse events. Conclusions: NLR is an independent predictive factor of early adverse events in uTBAD patients undergoing TEVAR.

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Section: Discussionmentioning

confidence: 54%

Elevated Preoperative Neutrophil-to-lymphocyte Ratio Predicts Early Adverse Outcomes in Uncomplicated Type B Aortic Dissection Undergoing TEVAR

Zhu

Zhang

Liang

et al. 2020

Preprint

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“…Furthermore, Jeong-ju et al [ 30 ] highlighted that a high NLR is an independent risk factor for poor prognosis in patients with primary cholangitis ( P < .01), and Lou et al [ 31 ] found that an NLR > 11 had important predictive value for the weaning failure of ICU patients ( P < .001). Zhou et al [ 32 ] has revealed that NLR > 6.5 often indicates the occurrence of a strangulated inguinal hernia in patients with inguinal hernia ( P < .001), and Ali et al [ 33 ] suggest that a preoperative NLR > 5 is an independent predictive marker of 30 day morbidity in ruptured abdominal aortic aneurysms ( P = .02).…”

Section: Discussionmentioning

confidence: 99%

Prognostic significance of the neutrophil-to-lymphocyte ratio with distal cholangiocarcinoma patients

Kang²,

Wang³

et al. 2020

Medicine

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Background: The present study aimed to investigate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in distal cholangiocarcinoma (DCC) following radical surgery. Methods: The clinicopathological data of 59 patients with DCC were retrospectively reviewed. Patients were treated by radical surgery and diagnosed by postoperative pathology at the Second Affiliated Hospital of Kunming Medical University (Yunnan, China), between July 2015 and December 2017. The optimal cut-off value for the NLR was determined by generating receiver operating characteristic (ROC) curves. Kaplan–Meier survival analysis and Cox proportional hazards models were used to determine the risk factors and independent risk factors influencing the prognosis of patients with DCC. Results: According to the ROC curve, the optimal cut-off value for the NLR was 2.933. The results of Kaplan–Meier survival analysis and the Cox proportional hazards model showed that carbohydrate antigen 125, NLR, perineural, vascular and fat invasion, regional lymph node metastasis, and the American Joint Committee on Cancer stage were risk factors for DCC; the only independent risk factor to affect the prognosis of DCC patients was the NLR. Conclusions: The preoperative NLR plays an important guiding role in evaluating the prognosis of patients with DCC, and an increase in the NLR is associated with poor patient prognosis.

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“…There are several studies investigating the contribution of inflammation in the formation of aortic aneurysm and rupture pathogenesis (11,17). Sbarouni et al (11) compared NLR, PLR rates in patients with acute aortic dissection (AAD) with control patients consisting of uncomplicated aortic aneurysms and healthy volunteers in a study they conducted.…”

Section: Discussionmentioning

confidence: 99%

“…Morello et al reported that WBC and platelet count will help in risk assessment of patients with low diagnosis probability in predicting AAD (18). Kordzadeh et al; reported that high NLR is an independent marker in predicting mortality in the first 30 days in cases with a ruptured abdominal aortic aneurysm (17). In our study, when compared to Group 1, it was found that the value of NLR (p = 0.029) was higher in Group 2 and this situation had a statistically significant difference.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Blood Biochemistry and Hematological Parameters on the Development of Pseudoaneurysm

Tunçay¹,

Özmen²,

Elçik³

et al. 2020

Kocatepe Tıp Dergisi

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Koroner arter hastalığı halen önde gelen sağlık sorunlarından biridir. Bu durum, kalp hastalıkları için tanı ve tedavi prosedürlerinde artışa sebep olmaktadır. Bununla birlikte, bu prosedürlerle ilişkili komplikasyonlarda da artışa sebep olmaktadır. Bu komplikasyonlardan biri psödoanevrizmalardır. Bu çalışmada, kliniğimizde psödoanevrizma ameliyatı geçiren hastalarda koroner anjiyografiden önce alınan periferik tam kan sayımlarının sonuçlarına göre psödoanevrizmanın gelişimini öngörmede hematolojik ve biyokimyasal parametrelerin yararlı olup olmayacağını tartışmayı amaçladık. GEREÇ VE YÖNTEM: Ocak 2017-Aralık 2019 tarihleri arasında hastanemizde koroner arter hastalığı ön tanısı ile elektif koroner anjiyografi yapılan 7368 hastanın verileri retrospektif olarak incelendi. Çalışmamıza dahil edilme kriterlerini karşılayan 88 hastanın verileri incelendi. BULGULAR: Psödoanevrizma erkek cinsiyet(%60), sağ alt ekstremite(%76.4) ve ana femoral arterde(%71.4) daha sıktı. Grup 1 ile karşılaştırıldığında psödoanevrizma gelişen Grup 2'de işlemden önce beyaz küre sayısı (WBC) (p: 0.042) ve Nötrofil lenfosit oranı (NLR) (p: 0.029) değerleri ve kan üre azotu (BUN) (p:0.050) yüksekti, Hemoglobin (Hb) (p<0.001), hematokrit htc(p<0.001), albumin(p: 0.026) değerleri düşüktü ve istatistiksel olarak anlamlı fark vardı. Platelet Pletekrit Oranı (PPR) (p: 0.205), Platelet Nötrofil Oranı (PNR)(p: 0.205), platelet(p: 0.103), total protein(p: 0.061), kreatin (p:0.060) ve Platekrit(p: 0.151) değerleri arasında istatistiksel olarak anlamlı bir fark yoktu.

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Neutrophil to lymphocyte ratio (NLR) of five predicts 30-day morbidity in ruptured abdominal aortic aneurysms (rAAA): A retrospective cohort study

Abstract: A preoperative NLR >5 is an independent predictive marker of 30d morbidity in rAAAs. This appears to be in line with earlier literature demonstrating similar outcome in the elective group of abdominal aortic aneurysm.

Cited by 39 publications

References 21 publications

Elevated Preoperative Neutrophil-to-lymphocyte Ratio Predicts Early Adverse Outcomes in Uncomplicated Type B Aortic Dissection Undergoing TEVAR

Elevated Preoperative Neutrophil-to-lymphocyte Ratio Predicts Early Adverse Outcomes in Uncomplicated Type B Aortic Dissection Undergoing TEVAR

Prognostic significance of the neutrophil-to-lymphocyte ratio with distal cholangiocarcinoma patients

The Effect of Blood Biochemistry and Hematological Parameters on the Development of Pseudoaneurysm

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