Since Thailand's first census 100 years ago, its patterns of illness, mortality and fertility have been transformed. Mortality and fertility fell very rapidly in the first 70 years as infectious diseases receded. Healthy childhood and safe motherhood were key benefits. Successive cohorts grew taller, and previously rare chronic diseases became common as families became smaller, incomes rose, people urbanised and the population aged.Dengue and tuberculosis remain major problems, and in recent decades, HIV/ AIDS has become an important cause of mortality among young adults. Traffic injury has become a major threat, and unfamiliar problems such as obesity, anxiety and depression are becoming widespread in Thailand.These changes have been the focus of a large multidisciplinary study of the Thai health-risk transition funded by the Wellcome Trust and the NH&MRC since 2004, with strong support from senior Thai government officials. The study focuses on the transition of both health risks and outcomes in the Thai population. Guided by conceptual advances in Professor Tony McMichael's approach to population health, it looks beyond the proximate, searching for multilevel drivers of changes under way and the sequences and mediators of transitions. Here, we outline the overall study design − with retrospective and prospective components − including an ongoing cohort study of nearly 90,000 adults already followed for eight years. Progress is summarised and future prospects reviewed.
Health of People, Places and Planet
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